We provided some ways of distinguishing RVO patients in practice and introduced the vasoactivity
of the vein itself and the possible involvement of vasoconstrictors such as ET-1 for the pathogenesis of RVO through our clinical studies, some animal experiments, and recent literatures.
Histamine is the principal vasoactive mediator and combined histamine-1 and -2 receptor responses are required for the full expression of histamine vasoactivity
, including immediate vasodilation, alteration in vasopermeability, plasma extravasation, and dermal sensory nerve stimulation [69-71].
Friedman, "HBOC vasoactivity
: interplay between nitric oxide scavenging and capacity to generate bioactive nitric oxide species," Antioxidants and Redox Signaling, vol.
Our in vitro studies of vessel vasoactivity
showed improved vasodilatation response after insulin stimulation in the young SHR treated with PIO.
These catacholamines are secreted during periods of stress allowing for enhanced vasoactivity
and altered myocardial function.
Mullan, "Characteristics of the in vitro vasoactivity
of [beta]-amyloid peptides," Experimental Neurology, vol.
The effect of concentration on vasoactivity
of bupivacaine and lignocaine.
That is to say, we have not assessed vasoactivity
changes, or impacts on diabetic/metabolic complications, or numerous other disease pathways that are clearly altered by PM exposure (Araujo et al.
Atherothrombotic events due to vasoactivity
, inflammation and also lipids may affect platelet function.
The first study used a vasoactivity
test that employed transient ischaemia generated by controlled arterial cuff occlusion (5).
After endothelial cell seeding, the artificial artery had a burst pressure of 2,000 mmHg and exhibited serotonin and endothelin-1 vasoactivity
. Patency of the artery was maintained for four weeks after carotid implantation in an animal model (Niklason et al 1999).
(17) There exist opportunities to further investigate nitric-oxide bioactivity as suggested by Bonaventura which include testing of arterial and venous RBC S-nitrosohemoglobin as a diagnostic indicator for transfusion; assaying hemoglobin re-nitrosylation treatment of stored RBCs; verification of normalized RBC rheology before transfusions; and verification of normalized RBC vasoactivity
prior to transfusion.