vasoactive intestinal polypeptide

polypeptide

 [pol″e-pep´tīd]

a peptide containing two or more amino acids linked by a peptide bond; called dipeptide, tripeptide, etc., depending on the number of amino acids present.

vasoactive intestinal polypeptide see vasoactive intestinal polypeptide.

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vasoactive

 [vas″o-ak´tiv]

exerting an effect upon the caliber of blood vessels.

vasoactive intestinal polypeptide (VIP) a peptide hormone that, in addition to its vasoactive properties, stimulates intestinal secretion of water and electrolytes, inhibits gastric secretion, promotes glycogenesis, causes hyperglycemia, and stimulates production of pancreatic juice. See also vipoma.

va·so·ac·tive in·tes·ti·nal pol·y·pep·tide (VIP),

a polypeptide hormone secreted most commonly by non-β islet cell tumors of the pancreas; VIP increases the rate of glycogenolysis and stimulates pancreatic bicarbonate secretion; excess production causes copious watery diarrhea and fecal electrolyte loss, with hypokalemia and hypochlorhydria.

Synonym(s): vasoactive intestinal peptide

vasoactive intestinal polypeptide (VIP)

a glucagon-secretin hormone found in the pancreas, intestine, and central nervous system. The hormone stimulates insulin and glucagon release. Gastric secretion, gastric motility, and peripheral vasodilation, as well as hyperglycemia by hepatic glycogenolysis, are inhibited. See also VIPoma.

va·so·ac·tive in·tes·ti·nal pol·y·pep·tide

(VIP) (vā'sō-ak'tiv in-tes'ti-năl pol'ē-pep'tīd)

A polypeptide hormone secreted by the infesting non-beta islet cell tumors of the pancreas. VIP inhibits gastric acid secretion, stimulates intestinal secretions, and replaces most gastrointestinal sphincters.
Compare: bioregulator

va·so·ac·tive in·tes·ti·nal pol·y·pep·tide

(VIP) (vā'sō-ak'tiv in-tes'ti-năl pol'ē-pep'tīd)

Polypeptide hormone secreted most commonly by non-β islet cell tumors of the pancreas; excess production causes copious watery diarrhea and fecal electrolyte loss.