In health, the vascular endothelium
maintains appropriate vascular wall tension and permeability of the blood vessel; maintains an anticoagulant, antithrombotic, profibrinolytic milieu which also inhibits immune cell adhesion and activation; and maintains and promotes appropriate vascular remodeling.
plays a key role in maintaining normal function of the vasculature (Bian and Toda 1988).
Our three proprietary RNAi delivery systems, AtuPLEX(TM), DACC and DBTC, deliver effective doses of RNAi to key intracellular targets in vascular endothelium
, lung and liver respectively, and provide our partners with a growing range of solutions to overcome their delivery challenges.
Localised egress of neutrophils from the circulation requires up-regulation of the expression of adhesion molecules on, and presentation of, chemoattractants by vascular endothelium
Several authors have investigated vascular invasion associated with MPUC, using immunohistochemical markers for vascular endothelium
In conclusion, the results of the present study show that the vasorelaxant effects of testosterone in sheep coronary arteries are mediated via the vascular endothelium
in the male group.
Endothelin (ET-1) is an amino acid peptide produced by the vascular endothelium
and increases angiotensin II, aldosterone, antidiuretic hormone, thrombin, and reactive oxygen species.
The topic include reasons for the variation in red wine phenolics, methods for determining natural antioxidants, enhancing the safety and healthiness by selected microbial starters, whether oak aging improves the antioxidant activity of red wines, red wine and vascular endothelium
, kidney protection by enhancing the antioxidant defense system, authentication and traceability studies on wine, and dielectric properties and wines impasses.
When salt is used in irrationally higher quantities it reduces body spaces along with the temperatures at different body levels including spaces in cardiac vascular endothelium
The mechanisms that have been considered to cause DHF include, antibody-dependent enhancement (ADE) of infection, dengue virus NS 1-antibodies cross-reacting with vascular endothelium
(a type of autoimmune phenomenon), immune complex disease, complement and its products, memory T cells, various soluble mediators including cytokines resulting in "Cytokine Tsunami", selection of virulent strains and virus virulence, etc.
Any impairment made to the vascular endothelium
may result in vascular dysfunctions.
Nitric oxide (NO), a diffusible intercellular messenger, is produced by most mammalian cells including vascular endothelium
, neurons, smooth muscle cells, macrophages, neutrophils, platelets and epithelium .