vascular endothelium


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vascular endothelium

the endothelium that lines the blood vessels.

vascular endothelium

The simple squamous epithelial tissue lining the blood vessels. It is a semipermeable barrier between the blood and the vascular smooth muscle, produces vasodilator chemicals, and may inhibit vasoconstrictor substances. Damage to the endothelium leads to increased production of prostaglandins and stimulates blood clotting.

tunica intima

single layer of specialized cells on a basement membrane forming the lining membrane of the entire vascular system (including heart and lymphatics); acts as interface between blood (within vascular system) and extravascular tissues; non-thrombogenic surface that does not normally react with plasma clotting factors and platelets (i.e. clots only form on it in presence of vascular/haematological pathology); regulates levels of circulating vasoactive chemicals (e.g. bradykinin, serotonin [5-HT], angiotensin); controls tissue perfusion (by releasing nitric oxide, prostacyclin and endothelin) by affecting vasomotor tone and platelet function
References in periodicals archive ?
In health, the vascular endothelium maintains appropriate vascular wall tension and permeability of the blood vessel; maintains an anticoagulant, antithrombotic, profibrinolytic milieu which also inhibits immune cell adhesion and activation; and maintains and promotes appropriate vascular remodeling.
Vascular endothelium plays a key role in maintaining normal function of the vasculature (Bian and Toda 1988).
Our three proprietary RNAi delivery systems, AtuPLEX(TM), DACC and DBTC, deliver effective doses of RNAi to key intracellular targets in vascular endothelium, lung and liver respectively, and provide our partners with a growing range of solutions to overcome their delivery challenges.
Localised egress of neutrophils from the circulation requires up-regulation of the expression of adhesion molecules on, and presentation of, chemoattractants by vascular endothelium.
Several authors have investigated vascular invasion associated with MPUC, using immunohistochemical markers for vascular endothelium.
In conclusion, the results of the present study show that the vasorelaxant effects of testosterone in sheep coronary arteries are mediated via the vascular endothelium in the male group.
Endothelin (ET-1) is an amino acid peptide produced by the vascular endothelium and increases angiotensin II, aldosterone, antidiuretic hormone, thrombin, and reactive oxygen species.
The topic include reasons for the variation in red wine phenolics, methods for determining natural antioxidants, enhancing the safety and healthiness by selected microbial starters, whether oak aging improves the antioxidant activity of red wines, red wine and vascular endothelium, kidney protection by enhancing the antioxidant defense system, authentication and traceability studies on wine, and dielectric properties and wines impasses.
When salt is used in irrationally higher quantities it reduces body spaces along with the temperatures at different body levels including spaces in cardiac vascular endothelium.
The mechanisms that have been considered to cause DHF include, antibody-dependent enhancement (ADE) of infection, dengue virus NS 1-antibodies cross-reacting with vascular endothelium (a type of autoimmune phenomenon), immune complex disease, complement and its products, memory T cells, various soluble mediators including cytokines resulting in "Cytokine Tsunami", selection of virulent strains and virus virulence, etc.
Any impairment made to the vascular endothelium may result in vascular dysfunctions.
Nitric oxide (NO), a diffusible intercellular messenger, is produced by most mammalian cells including vascular endothelium, neurons, smooth muscle cells, macrophages, neutrophils, platelets and epithelium [4].

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