vaccinia

(redirected from variola vaccinia)
Also found in: Dictionary, Thesaurus, Encyclopedia.
Related to variola vaccinia: variola vaccine

vaccinia

 [vak-sin´e-ah]
the cutaneous and sometimes systemic reactions associated with vaccination with smallpox vaccine. See also cowpox and paravaccinia.
vaccinia gangreno´sa generalized vaccinia with failure to develop antibodies against the virus (due to agammaglobulinemia), with spreading necrosis at the site and metastasis of lesions throughout the body.
generalized vaccinia a condition of widespread vaccinial lesions resulting from sensitivity response to smallpox vaccination and delayed production of neutralizing antibodies.
progressive vaccinia vaccinia gangrenosa.

vac·cin·i·a

(vak-sin'ē-ă),
An infection, primarily local and limited to the site of inoculation, induced in humans by inoculation with the vaccinia virus, type species in the genus Orthopoxvirus (family Poxviridae) to confer resistance to smallpox. On about the third day after this vaccination, papules form at the site of inoculation, which are transformed into umbilicated vesicles and later pustules; they then dry up, and the scab falls off on about the 21st day, leaving a pitted scar; in some cases there are more or less marked constitutional disturbances. Because of the global elimination of smallpox, routine vaccination is not now practiced.
[L. vaccinus, relating to a cow, fr. vacca, a cow]

vaccinia

(văk-sĭn′ē-ə)
n.
1. See cowpox.
2. The usually mild, cutaneous and sometimes systemic reaction in individuals who have been inoculated with smallpox vaccine.

vac·cin′i·al adj.

vac·cin·i·a

(vak-sin'ē-ă)
An infection, primarily local and limited to the site of inoculation, induced in humans by inoculation with the vaccinia virus, type species in the genus Orthopoxvirus to confer resistance to smallpox. Because of the global elimination of smallpox, routine vaccination is not now practiced.
[L. vaccinus, relating to a cow, fr. vacca, a cow]

vaccinia

A mild disease, acquired from the udders of cows, that causes blisters on the hands but no significant general upset. The disease is of historic importance. From knowledge of it, Edward Jenner developed vaccination against SMALLPOX. Also known as cowpox.