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Literature reveals that the presence of varicose vein in the limited epidural space as an underlying cause of sciatica has been reported in some papers previously, but very rare reports of sciatica due to idiopathic epidural varicosis (without any underlying disease) have been ever done.
Several mechanisms for secondary epidural varicosis have been proposed, but none of them confirmed for primary cases.
Although in idiopathic and symptomatic epidural varicosis, some authors proposed coagulative ablation, the preferred approach is surgical resection of the varicose vein (as we did) and generally, long-term favourable outcomes have been reported.
The researchers examined healthy human veins and varicose veins to identify genes in the vein's smooth muscle cells that may be involved in the development of varicosis
. Healthy vessels and varicose vessels were compared and inactive MGP was identified in the development of varicosis