vardenafil


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Related to vardenafil: sildenafil, tadalafil

vardenafil

(vär-dĕn′ə-fĭl)
n.
A drug that inhibits phosphodiesterase, C23H32N6O4S, used in its hydrochloride form to treat erectile dysfunction by increasing the level of cyclic GMP, which increases blood flow to the erectile tissues.

vardenafil

an impotence agent.
indication This drug is used to treat erectile dysfunction.
contraindications Known hypersensitivity to this drug prohibits its use. Alpha-blockers or nitrates prohibit should not be coadministered with this drug.
adverse effects Adverse effects of this drug include hypertension, conjunctivitis, tinnitus, photophobia, diminished vision, glaucoma, abnormal ejaculation, priapism, myalgia, arthralgia, neck pain, rhinitis, sinusitis, dyspnea, pharyngitis, epistaxis, rash, gastroesophageal reflux disease, and increased gamma glutamyl transpeptidase. Life-threatening side effects include myocardial infarction and cardiovascular collapse. Common side effects include headache, flushing dizziness, and insomnia.
A cGMP-specific phosphodiesterase type 5 inhibitor used to manage erectile dysfunction, taken ±1 hour before anticipated sexual activity; it is apparently effective for diabetics
Adverse effects Headache, dyspepsia, nausea, rhinitis

vardenafil

A selective inhibitor of phosphodiesterase type 5, the enzyme in the penis that limits the action of nitric oxide in promoting erection. (See SILDENAFIL CITRATE for fuller account). The drug is said to be effective more rapidly than Viagra. A brand name, presumably selected with the irresistible necessity for humour, is Levitra.
References in periodicals archive ?
The effects of different PDE-5 inhibitors (sildenafil, vardenafil, and tadalafil) and PDE-4 inhibitors (rolipram and RP 73401) with increasing concentrations on the tension induced by norepinephrine were analyzed by using the organ bath technique.
Vardenafil acted in synergy with inhaled nitric oxide, permitted nitric oxide reduction and discontinuation and proved to be effective as a single, long-term treatment for pulmonary hypertension.
9) In 2003, two additional oral PDE-5 inhibitors were approved by the Food and Drug Administration: (1) vardenafil (10) and (2) tadalafil.
For the time being, there is no evidence that NAION occurred more frequently in men taking sildenafil, tadalfil, or vardenafil than in men of similar age and health who did not take these medications.
Sildenafil and vardenafil are virtually identical in efficacy and duration of action.
Called phosphodiesterase-5 inhibitors, or PDE-5 inhibitors, they are sildenafil (Viagra), made by Pfizer; vardenafil (Levitra), from Bayer and GlaxoSmithKline; and tadalafil (Cialis), made by Lilly ICOS.
If the situation is not urgent, wait for the new medication Vardenafil (LaVetra), which is now scheduled for release sometime in the first half of 2003.
Vardenafil and Cialis are being tested for safety and effectiveness.
Otro inhibidor de la fosfodiesterasa-5 que entrara al mercado nacional este ano es el vardenafil, producido por Bayer, y mas eficaz en dosis equivalentes que su pariente el Viagra.
GSK has signed similar deals recently with Japan's Shionogi for several early stage products and Germany's Bayer for its impotence drug vardenafil.
Bayer Corporation has submitted a New Drug Application (NDA) for vardenafil, an investigational compound for the improvement of erectile function, to the U.