vardenafil


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Related to vardenafil: sildenafil, tadalafil

vardenafil

(vär-dĕn′ə-fĭl)
n.
A drug that inhibits phosphodiesterase, C23H32N6O4S, used in its hydrochloride form to treat erectile dysfunction by increasing the level of cyclic GMP, which increases blood flow to the erectile tissues.

vardenafil

an impotence agent.
indication This drug is used to treat erectile dysfunction.
contraindications Known hypersensitivity to this drug prohibits its use. Alpha-blockers or nitrates prohibit should not be coadministered with this drug.
adverse effects Adverse effects of this drug include hypertension, conjunctivitis, tinnitus, photophobia, diminished vision, glaucoma, abnormal ejaculation, priapism, myalgia, arthralgia, neck pain, rhinitis, sinusitis, dyspnea, pharyngitis, epistaxis, rash, gastroesophageal reflux disease, and increased gamma glutamyl transpeptidase. Life-threatening side effects include myocardial infarction and cardiovascular collapse. Common side effects include headache, flushing dizziness, and insomnia.
A cGMP-specific phosphodiesterase type 5 inhibitor used to manage erectile dysfunction, taken ±1 hour before anticipated sexual activity; it is apparently effective for diabetics
Adverse effects Headache, dyspepsia, nausea, rhinitis

vardenafil

A selective inhibitor of phosphodiesterase type 5, the enzyme in the penis that limits the action of nitric oxide in promoting erection. (See SILDENAFIL CITRATE for fuller account). The drug is said to be effective more rapidly than Viagra. A brand name, presumably selected with the irresistible necessity for humour, is Levitra.
References in periodicals archive ?
Vardenafil acted in synergy with inhaled nitric oxide, permitted nitric oxide reduction and discontinuation and proved to be effective as a single, long-term treatment for pulmonary hypertension.
9) In 2003, two additional oral PDE-5 inhibitors were approved by the Food and Drug Administration: (1) vardenafil (10) and (2) tadalafil.
Sildenafil and vardenafil are virtually identical in efficacy and duration of action.
Vardenafil and Cialis are being tested for safety and effectiveness.
GSK has signed similar deals recently with Japan's Shionogi for several early stage products and Germany's Bayer for its impotence drug vardenafil.
Bayer Corporation has submitted a New Drug Application (NDA) for vardenafil, an investigational compound for the improvement of erectile function, to the U.
Bayer's medium-term product pipeline includes Vardenafil, an impotence treatment that will challenge Pfizer's Viagra, a new class of antibiotics and several cancer medicines.
Cialis is currently being tested in America and is said to work quicker and last longer than Viagra, while Vardenafil looks to be at least as effective as Viagra but to have far fewer side-effects.
At follow-up appointments, the patient reported significant ED improvement with the low-dose vardenafil and no cluster headache bouts.
McGwin said the relationship was strongest for men reporting use of sildenafil (Viagra) over those who used tadalafil (Cialis) or vardenafil (Levitra), a finding he attributed in part to a small sample size for both of the latter drugs.