Overexpression of human mitochondrial valyl
tRNA synthetase can partially restore levels of cognate mt-[tRNA.sup.Val] carrying the pathogenic C25U mutation.
The 12S/16S region starts near the phenylalanyl tRNA end of the 12S rRNA gene, and runs through the valyl
tRNA gene to near the leucyl tRNA end of the 16S rRNA gene.
Another popular FOSHU functional ingredient is a sardine peptide (valyl
tyrosine), also targeted toward blood pressure maintenance.