The linearity of the method was evaluated by analyzing eight solutions in the concentration ranges 50-350 [micro]g/mL for each solution of magnesium valproate and its related impurities.
The selectivity of the method was evaluated by injecting blank matrix, each individual impurity, magnesium valproate standard solution, and spiked solution to check the interference of the diluent as well as the standard solution on each other.
The developed UPLC method shows a good separation of magnesium valproate to its impurities.
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