valproate

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valproate

 [val-pro´āt]
a salt of valproic acid with anticonvulsant activity similar to that of the acid.

valproate

(văl-prō′āt)
n.
A salt or ester of valproic acid, especially the sodium form, which is used as an anticonvulsant.
References in periodicals archive ?
The linearity of the method was evaluated by analyzing eight solutions in the concentration ranges 50-350 [micro]g/mL for each solution of magnesium valproate and its related impurities.
The selectivity of the method was evaluated by injecting blank matrix, each individual impurity, magnesium valproate standard solution, and spiked solution to check the interference of the diluent as well as the standard solution on each other.
The developed UPLC method shows a good separation of magnesium valproate to its impurities.
Guidolin, "Clinical efficacy and tolerability of magnesium valproate as monotherapy in patients with generalised or partial epilepsy: a nonblinded study of 320 patients," Clinical Drug Investigation, vol.
Di Giovanni, "Comparative study between sodium valproate and magnesium valproate in the treatment of patients with epileptic seizures," Rivista di Neurologia, vol.
Popovic et al., "Lamotrigine and valproate pharmacokinetics interactions in epileptic patients," European Journal of Drug Metabolism and Pharmacokinetics, vol.
Liu, "Determination of magnesium and sodium valproate in serum by high performance liquid chromatography after precolumn derivatization," Yaowu Fenxi Zazhi, vol.
Xiao, "Determination of magnesium valproate in serum by gas chromatography," Se Pu, vol.
Shah, "Validation of an analytical method for assay of magnesium valproate by gas chromatography," International Journal of ChemTech Research, vol.
Xu, "Determination of sodium valproate in human serum by HPLC," Zhongguo Yaoye, vol.