In June 2011, the FDA issued an alert when interim results of this study found that at age 3 years, children exposed to valproate
had lower scores on cognitive tests, information that was added to the labels at that time.
Children of women who used valproate
during pregnancy had a higher risk of autism spectrum disorder and childhood autism compared with children of women who did not use valproate
," the researchers wrote.
The authors point out that other research has pointed to the potentially harmful effects of valproate
on the developing fetus, and that the findings of the current study back other preliminary research.
, hyperandrogenism and altered ovarian function in Indian women with epilepsy: a prospective study.
In 2010, he received travel support from Sanofi-Aventis, a manufacturer of valproate
binding sites on plasma proteins are easily saturable, however, and at plasma valproate
concentrations modestly greater than the therapeutic maximum, the fraction of total valproate
bound to protein starts to decrease.
syndrome: is there a recognisable phenotype?
The new study is important because it's the largest to show a connection between valproate
and diminished IQ.
The primary objective of the extension phase was to assess the long-term safety and tolerability of ABILIFY in combination with lithium or valproate
While from the same chemical class as valproate
His GP has tried lithium and valproate
semi-sodium but he still has highs and lows and we are all suffering.
Depacon--sold as valproate
by generic drugmakers Abraxis Pharma and Bedford--was best for those with generalized onset seizures and difficult to classify cases, the British researchers said.