valinomycin


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val·in·o·my·cin

(val'i-nō-mī'sin),
Cyclododecadepsipeptide ionophore antibiotic derived from Streptomyces fulvissius; used as an insecticide and nematocide.

valinomycin

ionophore consisting of a cyclic trimer of tetrapeptides. Specifically transports potassium ions across cell membranes. Inhibitor of oxidative phosphorylation due to its action in antagonizing the proton motive force.
References in periodicals archive ?
The mitochondrial toxin produced by Streptomyces griseus strains isolated from indoor environment is valinomycin.
Potassium ion concentration on the LX20 is determined by indirect potentiometry, using an ISE with a valinomycin ionophore (1).
The ISE chemistry uses an electrode containing a valinomycin membrane in conjunction with a reference electrode to determine potassium activity via indirect potentiometry.
To avoid interference from native ammonia in the sample, an additional ammonium ISE is used as well as a potassium ISE based on the ionophore valinomycin to compensate for interference from potassium ions at the ammonium sensors.