Survival in patients with glioblastoma receiving valganciclovir
Incidence and characterization of cytomegalovirus resistance mutations among pediatric solid organ transplant patients who received valganciclovir
Although the longer treatment with valganciclovir
was expensive, the cost was largely offset by reducing the number of patients who contracted CMV disease, which in turn averted its long-term adverse consequences.
Durante los diez dias siguientes se mantuvo afebril por lo que siguio control en la consulta de trasplantes y acudio a ponerse el tratamiento de forma ambulatoria hasta finalizar pauta intravenosa y pasar a valganciclovir
Anti-CMV therapy exists in various forms (intravenous, oral and intravitreal) and includes ganciclovir, valganciclovir
, foscarnet and cidofovir.
The study's results suggest that valganciclovir
may be an effective and safe way to both prevent and treat these HHV-8-related diseases, he said at the annual meeting of the Infectious Diseases Society of America.
In a double-blind clinical trial of valganciclovir
involving 42 patients with glioblastoma, an exploratory analysis of 22 patients receiving at least six months of antiviral therapy showed 50% overall survival at two years compared with 20.
CMV has been called the 'neglected disease of the AIDS pandemic', in part because of limited access to treatment, especially in the developing world, where localised intra-ocular ganciclovir implants and systemic oral valganciclovir
are unavailable or too costly.
Treatment was changed to oral valganciclovir
, 900 mg 2x/d for 20 days, upon discharge.
open-house-contracts" for the drug valganciclovir
drug (pharmaceutical form powder for oral solution).
The drug valganciclovir
can eradicate active CMV infection.
TREATMENT: THE URGENT NEED FOR VALGANCICLOVIR
PRICE REDUCTION IN SA FOR CMV TREATMENT IN HIV PATIENTS