Many people use various antispasmodic agents like drotaverine, hyoscine, dicyclomine and valethamate bromide
to accelerate the first stage of labour, thereby reducing the sufferings of labouring mother.
Comparison of Hyoscine-Butylbromide and Valethamate Bromide
in shortening the duration of labour.
In the present case, combination of estrogen, Valethamate bromide
, prostaglandin and corticosteroid was used for cervical dilation.
As per requirement artificial rupture of membrane and augmentation of labour was done with oxytocin drip and smooth muscle relaxation (Drotaverine hydrochloride, Valethamate bromide
In order to dilate the cervix, animal was administered with Intalyte (a) 1000 ml, slow iv, Valethamate bromide
50 mg i/m, Cloprostenol sodium 500[micro]g i/m, Dexamethasone 30 mg i/m and Diethylstilboestrol 30 mg, i/m, in addition Calcium and magnesium borogluconate (inj.
Tiwari K et al (4) (2003) studied the effectiveness of Buscopan and valethamate bromide
on cervical dilatation with 300 cases using Buscopan intravenously with 40 mg dose as two divided doses.
Clinical cases presented for cervical dilatation have been tried with Valethamate bromide
, Dexamethasone or Prostaglandin therapies with varied results but there are no concrete recommendations regarding the treatment.
Critical evaluation of the efficacy of drotaverine hydrochloride with valethamate bromide
Similar results are found in this case wherein parturition was induced within 48 hours, using Valethamate bromide
and calcium to accelerate the ripening of the cervix and uterine inertia.
The drugs available are drotaverine hydrochloride, valethamate bromide
, hyoscine N-butyl bromide, hyalase.
The animal was treated with Antihistaminics (Anistamin (a) 4 ml i/m), Valethamate bromide
(Epidosin (b), 5 ml i/m), 5% Dextrose saline (450 ml i/v) and Oxytocin (Syntocinon (c) 2 ml i/v) along with Dextrose and 250 ml Calcium borogluconate i/v and the owner was asked to observe for any change.