valacyclovir


Also found in: Dictionary, Acronyms, Wikipedia.

valacyclovir

 [val″a-si´klo-vir]
an ester of acyclovir, to which it is metabolized; used as the hydrochloride salt as an antiviral agent in treatment of genital herpes and herpes zoster in patients who are not immunocompromised, administered orally.

valacyclovir

/val·a·cy·clo·vir/ (val″a-si´klo-vir) an ester of acyclovir, to which it is metabolized; used as the hydrochloride salt as an antiviral agent in the treatment of genital herpes and herpes zoster in immunocompetent adults.

valacyclovir

(văl′ə-sī′klō-vîr′)
n.
A nucleoside analog, C13H20N6O4, that is a prodrug of acyclovir and is used in its hydrochloride form to treat herpes simplex and herpes zoster infections.

valacyclovir

[val′a-si′klo-vir]
an ester of acyclovir, to which it is metabolized. The hydrochloride salt is used as an antiviral agent in treatment of genital herpes and herpes zoster in patients who are not immunocompromised. It is administered orally.

valacyclovir

Valtrex® Infectious disease An antiviral used for 1st episode/recurrent genital herpes and acute herpes zoster, which may ↓ risk of CMV infection after renal transplantation. See Dofetilide, Herpes simplex.

Valacyclovir

An oral antiviral drug that is available under the trade name Valtrex. The drug blocks the replication of the varicella zoster virus.
Mentioned in: Shingles
References in periodicals archive ?
Valacyclovir and acyclovir for suppression of shedding of herpes simplex virus in the genital tract.
In this report, we share a case of acute retinal necrosis that was completely controlled with oral valacyclovir therapy and discuss ARN treatment.
3% during valacyclovir treatment, a significant difference (relative risk, 0.
Common side effects with acyclovir, valacyclovir, and famciclovir include headache, skin rash, nausea, vomiting, and diarrhea.
Valacyclovir targets a different enzyme and works only in infected cells, whereas pritelivir has the advantage of protecting healthy cells while thwarting virus replication in infected cells, Rubsamen-Schaeff said.
RESULTS: In total, 162 patients were enrolled in the study and randomized into Valacyclovir and Famciclovir groups in 1:1 ratio.
The impressive improvement in response to valacyclovir documented in this study lends support to the viral hypothesis of mental illness, she said.
At this time, there isn't as much information on the safety of valacyclovir and famciclovir, but both are classified as class B agents by the FDA (no evidence of risk in humans), similar to the risk of acyclovir.
The herpetic infection had been treated with valacyclovir 1000 mg 3 times a day for 10 days with no scar formation.
Healing times for recurrences of herpes simplex virus 2 (HSV-2) for several doses of ASP2151 were significantly better than placebo and were comparable to valacyclovir, based on the results of a phase II randomized, double-blind study including 43 7 individuals.
I suggested that my friend's sister consider taking 500 mg a day of valacyclovir (Valtrex[R]) as this has been shown to reduce the number of herpes outbreaks (5) and reduce the chances of spreading the virus to one's sexual partner by 47%.
The antiviral drugs acyclovir, valacyclovir, and famciclovir may reduce symptoms if started within three days of getting the rash.