Because overexcited sympathetic function plays an important role in ischemic heart disease, the vagotonic
stimulation of administrated acetylcholinesterase inhibitors might also provide beneficial effects .
(2009) suggested that the use of beta-blockers and other cardiac medications, such as digitalis, which is vagotonic
, may mitigate adverse effects of PM on HRV.
AChEIs may potentially have vagotonic
effects on heart rate (i.e.
Pulmonary vein isolation for vagotonic
, adrenergic, and random episodes of paroxysmal atrial fibrillation.
Motion sickness (sea-sickness) is being defined as a neuro-vegetative syndrome with a reflex origin, especially vagotonic
that has the source in the vestibular apparatus.
Although digoxin has prominent vagotonic
effects, it is not very effective in decreasing the heart rate in the presence of enhanced sympathetic drive.