[USA], Apr 17 (ANI): Vaginal dryness
and painful intercourse are some of the common adverse events of post-breast cancer treatment therapies.
The publication reported that a self-administered vaginal suppository containing tamoxifen, dosed daily for one week followed by twice weekly for three months, administered to four healthy postmenopausal women with VVA showed significant improvements in reducing vaginal pH and vaginal dryness
without significant systemic absorption of tamoxifen.
Duchesnay USA, a pharmaceutical company specializing in women's health, announced that the Food and Drug Administration has approved its supplemental New Drug Application (sNDA) seeking to add moderate to severe vaginal dryness
, a symptom of vulvar and vaginal atrophy (WA), due to menopause, to the indication of Osphena (ospemifene).
Three of the most common causes include vulvodynia (chronic pain in the vulvar region), pelvic floor dysfunctions (issues with muscles, ligaments, and joints of the pelvic girdle), and vaginal atrophy (vaginal dryness
, tissue thinning, and mild incontinence).
Due to the low production of estrogen in the body, about 85% of women have symptoms such as hot flushes, bone loss, vaginal dryness
and shrinkage of tissues.
This US FDA application is based on the company's new safety and efficacy data acquired through a confirmatory phase 3 randomized, double blind, placebo-controlled multicenter study evaluating the efficacy and safety of ospemifene in patients with moderate to severe vaginal dryness
Common symptoms include hot flushes, night sweats, vaginal dryness
and low moods.
VVA can cause vaginal dryness
, itching, and soreness, and often leads to pain with sex and sexual dysfunction.
Targets are therefore menopausal women to relieve vaginal dryness
and mild stress incontinence, widening the web to include younger women to counteract the stretching during childbirth.
Any disruption in this ecosystem may result in inflammation, vaginal infection and vaginal dryness
,' she says.
Furthermore, several studies have demonstrated that HT has the potential to reduce vaginal dryness
NeoVirgin gel is created with natural ingredients in an effort to eliminate vaginal dryness
, narrow the vaginal walls, and increase sensitivity in the area.