vaginal candidiasis


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Related to vaginal candidiasis: Yeast infection, trichomoniasis

candidiasis

 [kan″dĭ-di´ah-sis]
infection by fungi of the genus Candida, generally C. albicans, most commonly involving the skin, oral mucosa (thrush), respiratory tract, or vagina; occasionally there is a systemic infection or endocarditis. It is most often associated with pregnancy, glycosuria, diabetes mellitus, or use of antibiotics. The Centers for Disease Control and Prevention has found that in the United States this condition is the fourth most common cause of nosocomial infections of the blood stream. Called also candidosis and moniliasis.

The most prominent symptom of vaginitis due to Candida infection is severe itching. Sexual transmission is unlikely. Intravaginal cream containing miconazole or clotrimazole, applied each night for one week, usually clears up the infection. Difficulty or pain with swallowing, or retrosternal pain, may indicate candidiasis of the esophagus. Systemic antifungal therapy is indicated for esophagitis and other more severe forms of the disease. Therapeutic options include ketoconazole, fluconazole, and amphotericin b. Chronic suppressive therapy is sometimes required for severely immunocompromised patients. The Infectious Disease Society of America has published “Practice Guidelines for the Treatment of Candidiasis” on their web site, http://www.idsociety.org.
atrophic candidiasis oral candidiasis marked by erythematous, pebbled patches on the hard or soft palate, buccal mucosa, and dorsal surface of the tongue, a complication of numerous different conditions such as vitamin deficiency, diabetes mellitus, or poorly fitting dentures. There are acute forms and a chronic form called denture stomatitis.
bronchopulmonary candidiasis candidiasis of the respiratory tree, occurring in a mild afebrile form manifested as chronic bronchitis, and in a usually fatal form resembling tuberculosis. Called also bronchocandidiasis.
chronic mucocutaneous candidiasis a group comprising a number of varying forms of Candida infection, marked by chronic candidiasis of the skin and nails and the mucous membranes of the mouth and vagina that is resistant to treatment; it may be localized or diffuse, is sometimes familial, and may be associated with disorders of the immune and endocrine systems.
endocardial candidiasis Candida endocarditis.
oral candidiasis thrush.
pulmonary candidiasis a type of fungal pneumonia caused by infection with Candida species, seen especially in immunocompromised patients or those with malignancies. Called also Candida pneumonia.
vaginal candidiasis (vulvovaginal candidiasis) candidal infection of the vagina, and usually also the vulva, commonly characterized by itching, creamy white discharge, vulvar redness and swelling, and dyspareunia. Called also Candida or candidal vaginitis and Candida or candidal vulvovaginitis.

vaginal candidiasis

vaginal candidiasis

Vaginal mycosis, vaginal thrush, vaginal yeast infection Gynecology Infection of the lower ♀ gentital tract with Candida spp, usually C albicans, a fungus normally found in the flora of the vagina, mouth, GI tract, skin–±25% of ♀ have Candida spp; Sx appear when the balance with other saprobes is changed, favoring candidal growth–eg, after antibiotics, especially tetracycline; related to estrogen-based OCs, DM, immunocompromise–eg, AIDS. See Candidiasis.
References in periodicals archive ?
Under the four different scenarios for use of laboratory testing associated with the evaluation of vaginal candidiasis, the estimated savings to the Fallon Health Care System would be: (1) $12,768 if no tests were performed; (2) $17,604 with a potassium hydroxide preparation alone; (3) $20,893 with a vaginal culture alone; and (4) $25,729 if both a potassium hydroxide preparation and vaginal culture were performed.
Table 51: Candidiasis Therapeutics Market, Global, Annual Cost of Treatment, Vaginal Candidiasis ($), 2002-2010 91
And, because low-dose doxycycline has no antimicrobial activity, it does not lead to vaginal candidiasis as do the tetracyclines, she noted.
Of significant note was the finding that in both studies vaginal candidiasis and photosensitivity were not observed in the patients treated with anti-inflammatory dose doxycycline.
Neither trial reported cases of phototoxicity or photosensitivity, and none of the female patients developed oral or vaginal candidiasis during treatment with anti-inflammatory--dose doxycycline, he emphasized.
The most frequently reported adverse events related to study treatment occurred in 2% of women and included vaginal pruritus, vaginal discharge, vaginal candidiasis and nausea.
In a randomized, double-blind, multicenter study, 284 women with recurrent vaginal candidiasis infections first underwent an open-label induction period in which all were given a total of three doses of fluconazole at 72-hour intervals with the aim of achieving clinical remission.
In addition, Anacor has a portfolio of other topical product candidates in development for the treatment of psoriasis, gingivitis, acne, vaginal candidiasis and tinea pedis.
He added that vaginal candidiasis is often diagnosed as herpes, particularly in college students.
The four most advanced product candidates, which are in or entering Phase III clinical trials, are under development for the treatment of Candida-associated diaper dermatitis, seborrheic dermatitis, fungal infections, including vaginal candidiasis and onychomycosis, and congenital ichthyosis.
It has been used during the first trimester for vaginal candidiasis without apparent harm and has been used at high doses in the third trimester for hypercortisolism in one patient without any harm to the infant.
During this year, the company launched a systemic treatment for menopausal symptoms, a new oral contraceptive and a local treatment for vaginal candidiasis licensed from the Italian company Recordati.