vivipara have demonstrated that the high frequency in cytoplasmatic vacuolation
is probably associated to the action of chemical substances that are released into the environment and Dyk et al.
Some tubules also showed areas of patchy necrosis with loss of brush border and vacuolation
implying thereby that tubular injury was not in fact fully reversed (Fig-2).
Exposure of CYP for 96 h caused glycogen vacuolation
congestion hemorrhage vacuolation
fatty infiltration and hepatic necrosis (Fig.
Vesicular clear vacuolation
seen in cytoplasm of secretory portion of eccrine sweat glands.
Basal layer showed focal vacuolation
and increased amount of melanin pigment (Fig.
The histopathological study of the brain showed neuronal losses and vacuolation
in brain tissues,  reported neuron necrosis in different region of the brain in mice.
The malacia was characterized by vacuolation
of neuropil associated with the presence of densely infiltrated polymorphonuclear cells, moderate amounts of Gitter cells (Figure 2D), lymphocytes, endothelial cell proliferation and Splendore-Hoeppli eosinophilic substance.
The general criteria to score damaged cells included hyperchromatic nuclei and cytoplasmic vacuolation
Research has shown that there was an increase in the number of blood vessels,, lymphatic vessels and vacuolation
of the cells.
The virus induced polykaryocytosis, which is characterized by the formation of large syncytia with nuclear and cytoplasmic vacuolation
, a phenomenon that is not reported in mammalian cells infected with other arboviruses.
The keratinocytes showed degenerative changes in the form of cytoplasmic vacuolation
, ballooning, and hyper-chromatic nuclei.
In bone marrow, megaloblastoid changes, multinuclearity, nuclear budding and bridging in erythroblasts, hypogranulation in granulocytic series, micromegakaryocytes, uninucleated and binucleated forms, and cytoplasmic vacuolation
in megakaryocytes were the common dysplastic features.