vacuolar myelopathy


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vacuolar myelopathy

Neurology A heterogeneous group of conditions characterized by spinal cord degeneration; VM occurs in up to 20% of AIDS Pts; it is most extensive in the lateral columns of the middle and lower thoracic segments. Cf Spongy degeneration.
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(1) The most common disease of spinal cord in HIV is the vacuolar myelopathy. (1) The type of neurological involvement in HIV depends on stage of immune dysfunctioning.
It is unlikely that any of the patients had HIV-associated vacuolar myelopathy since the characteristic lesions (hyperintensities in the posterior and lateral columns) were not noted on MRI.

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