vacuolar myelopathy


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vacuolar myelopathy

Neurology A heterogeneous group of conditions characterized by spinal cord degeneration; VM occurs in up to 20% of AIDS Pts; it is most extensive in the lateral columns of the middle and lower thoracic segments. Cf Spongy degeneration.
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1) The most common disease of spinal cord in HIV is the vacuolar myelopathy.
In spite of the benefits of antiretrovirals, some patients continue to develop AIDS-related complications such as mycobacterium avium complex (MAC) and tuberculosis, neurologic impairment from HIV neuropathy and HIV dementia, and vacuolar myelopathy of the spinal cord.
Other disorders that can arise from primary HIV infection in the CNS include minor cognitive motor disorder, delirium, aseptic meningitis, and vacuolar myelopathy "Psychotic disorders due to a general medical condition are [also] important to rule out.

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