c-Rel(redirected from v-rel reticuloendotheliosis viral oncogene homolog)
c-RelA member of the NF-kappaB family of transcription factors encoded by REL on chromosome 2p13-p12, which is distinguished by the presence of an N-terminal Rel homology domain.
c-Rel overexpression causes downregulation of EPHB2 (an ephrin receptor tyrosine kinase in the intestine), and is associated with a poor prognosis in colorectal carcinoma.
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