AKT2

(redirected from v-akt murine thymoma viral oncogene homolog)

AKT2

A gene on chromosome 19q13.1, which encodes a protein of the subfamily serine/threonine kinases containing SH2 (Src homology 2)-like domains, and phosphorylates several known proteins.

Molecular pathology
The gene is amplified and overexpressed in some primary ovarian tumours and pancreatic ductal carcinomas.
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[5] Human genes: AKT1, v-akt murine thymoma viral oncogene homolog 1; EGFR, epidermal growth factor receptor; KRAS, v-Ki-ras2 Kirsten rat sarcoma viral oncogene homolog; BRAF, v-raf murine sarcoma viral oncogene homolog B1; TP53, tumor protein p53; PDGFRA, platelet-derived growth factor receptor, [alpha] polypeptide.