(10.) Baxter SL, Pistilli M, Pujari SS, Liesegang TL, Suhler EB, Thorne JE, Foster CS, Jabs DA, Levy-Clarke GA, Nussenblatt RB, Rosenbaum JT, Kempen JH Risk of choroidal neovascularization among the uveitides
. Am J Ophthalmol 2013;156:468-477.
Laboratory testing was performed for infectious and noninfectious causes of uveitis, including syphilis, tuberculosis, cat-scratch disease, Lyme disease, toxoplasmosis, ANCA-associated uveitides
, systemic lupus erythematosus, and sarcoidosis.
Eight men and 5 women (22 affected eyes) with a median age of 30 years (range 20-38) and active immune-mediated uveitides
Behcet's uveitis (BU) is characterized by chronic panuveitis or posterior uveitis with necrotizing retinal vasculitis and tends to be more recurrent and sight threatening than other endogenous uveitides such as Vogt-Koyanagi-Harada (VKH) disease or HLA-B27-associated uveitis.
Previously, our analysis of immune cell types in active BU revealed that the predominant intraocular infiltrating cells were CD8+ T cells, whereas CD4+ T cells were the predominant infiltrating cells in patients with other uveitides .
Different autofluorescence patterns are reported in infectious and noninfectious uveitides as well as masquerade syndromes .
Generally, in posterior uveitides, hyperautofluorescence indicates disease activity while quiescent disease and areas of chorioretinal atrophy or scarring are hypoautofluorescent.
If anything, the sex differences in infectious uveitis are likely to be greater than in autoimmune disorders because exposure to infections involves behavioral and cultural issues not encountered with the other uveitides.
Women are uniquely affected by infectious uveitides. Vulnerability to HIV from infected partners exposes them to risk of cytomegalovirus retinitis.
To assess the effect of intravitreal bevacizumab injection (IVBI) for the treatment of macular edema due to infectious and noninfectious uveitides