uteroplacental insufficiency


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Related to uteroplacental insufficiency: IUGR

uteroplacental insufficiency

Inadequate blood flow through the placental intervillous spaces to enable sufficient transmission of nutrients, oxygen, and fetal wastes. It may be caused by diminished maternal cardiac output due to anemia, heart disease, regional anesthesia, or supine hypotension; vasoconstriction due to chronic or pregnancy-related hypertension or uterine overstimulation; vasospasm due to pregnancy-induced hypertension; vascular sclerosis due to maternal diabetes or collagen disease; or intrauterine infection. It increases the risk for intrauterine growth retardation.
See also: insufficiency
References in periodicals archive ?
Hale et al., "Uteroplacental insufficiency affects kidney VEGF expression in a model of IUGR with compensatory glomerular hypertrophy and hypertension," Early Human Development, vol.
Uteroplacental insufficiency increases apoptosis and alters p53 gene methylation in the full-term IUGR rat kidney.
However, the analysis done by Farrell et al 75 for reliability of early diastolic notch in uterine artery as predictor for uteroplacental insufficiency revealed a sensitivity of 88%.
Repeat Doppler on second week on Day 15 of admission was suggestive of uteroplacental insufficiency (Increased RI of umbilical artery) and absent uterine artery flow.
Severe degree of uteroplacental insufficiency in group B than in group A could be the reason for greater number of IUGR babies in group B.
The fetal and newborn benefits of delivery, rather than expectant management, at term include: a decrease in stillbirth and perinatal death rates, a decrease in admissions to the neonatal intensive care unit (NICU), a decrease in meconium-stained amniotic fluid and meconium aspiration syndrome, a decrease in low Apgar scores, and a decrease in problems related to uteroplacental insufficiency, including oligohydramnios.