The ex utero intrapartum procedure (EXIT), originally designed to improve cardiorespiratory stability via uteroplacental
bypass for treatment of tracheal occlusion during delivery, may improve the outlook for these infants.
Renin is synthesized and secreted into the blood exclusively by the juxtaglomerular cells of the kidney from prorenin, an inactive precursor, which is produced not only by the kidney, but by other tissues, including the adrenal glands, gonads, and the uteroplacental
(1) The development of a good uteroplacental
circulation is essential for the achievement of a normal pregnancy, when this mechanism fails abnormal vascular resistance pattern develops leading to a compromised foetus.
The prevailing theory is that maternal hypertension is a compensatory mechanism designed to overcome the reduction in uteroplacental
perfusion resulting from intravascular depletion and increased placental resistance.
We investigated 58 women with consecutive singleton physiological pregnancies (30 at term and 28 preterm), with normal flow velocimetry waveforms in the uteroplacental
vessels, whose delivery was between 27 and 42 weeks of gestation.
Here, the best (level I) evidence backs Doppler assessment, while other tests for decreased uteroplacental
blood flow that are supported by level I or level II evidence include estimated fetal weight by ultrasound, amniotic fluid assessments, nonstress tests (NSTs), and fetal biophysical profiles (FBPs).
It has been recorded that maternal uteroplacental
blood flow is decreased in pre-eclampsia, because there is maternal vasospasm.
It's worth emphasizing that uteroplacental
failure develops over time, and the amniotic fluid index becomes abnormal only after the process is fairly far along and fetal blood flow redistribution has become moderate to severe.
Intrauterine growth restriction was observed in 13% cases due to early diagnosis of oligohydramnios indicating uteroplacental
Nifedipine can cause maternal and fetal tachycardia, as well as hypotension in the mother and altered uteroplacental
blood flow to the fetus.
Sitting to avoid acute flexion as pressure of thighs on gravid uterus transiently reduces Uteroplacental
But the label, which was revised in April, now provides information about risk factors associated with uterine rupture, which may guide safer use of the drug in pregnancy The label now lists the major adverse effects of Cytotec's obstetric uses, including hyperstimulation of the uterus, which may progress to uterine tetany with marked impairment of uteroplacental
blood flow; uterine rupture (requiring surgical repair, hysterectomy, and/or salpingo-oophorectomy); or amniotic fluid embolism.