Uterine Sarcoma, Version 1.2016: Featured Updates to the NCCN Guidelines.
Non-puerperal uterine inversion in association with
uterine sarcoma: Case report in a 26-year-old and review of the literature.
The presence of cartilage in MMMT is considered a favorable prognostic factor.8
Uterine sarcoma accounts for 3-5% of all corpus uteri malignancies; undifferentiated
uterine sarcomas arise from the endometrium or myometrium, lacking any resemblance to normal endometrium and may show heterologous stromal elements in the form of cartilage, bone or rhabdomyoblasts.9 In our case the hyaline cartilage nodules were mostly located deep in the myometrium, close to the serosal surface and adjacent tissue exhibited foci of adenomyosis; the closest differential diagnosis ruminated was adenosarcoma.
In this particular case, the original intent was to address the patient's quality of life (colostomy and nephrostomy) as her prognosis was poor with metastatic
uterine sarcoma. However, she did not have any recurrence of her metastatic sarcoma after lung resection and presented with recurrent UTIs leading to recurrent encrustations of her pyelovesical bypass graft.
I hope by raising awareness of
uterine sarcoma I will help to save lives or, at the very least, extend lives.
The review determined that 1 in 350 women undergoing hysterectomy or myomectomy for fibroids may have an occult
uterine sarcoma, and that 1 in about 500 have an unsuspected leiomyosarcoma.
Endometrial cancer arises from the inner layer (endometrium) of the uterus, the origin of approximately 90% of uterine cancers, followed by
uterine sarcoma that arises from the outer layer (myometrium) (8%) and less frequent types of cancer (2%).
Uterine adenosarcoma is an extremely rare subtype of
uterine sarcoma, which represents only 5.5 to 9% of all
uterine sarcomas [1,2].
FDG PET is clinically useful for the staging of
uterine sarcoma [13].
Singh, "Clinical characteristics differentiating
uterine sarcoma and fibroids," Journal of the Society of Laparoendoscopic Surgeons, vol.
The computed tomography (CT) scan showed enlargement of the uterus, which led us to suspect
uterine sarcoma and para-aortic lymph node metastasis that infiltrated the iliopsoas.
From the detailed literature reviews of
uterine sarcoma with synchronous occurrence of carcinoma as indicated in Table 3, the present case is the first case with synchronous occurrence of leiomyosarcoma and adenocarcinoma in situ in the cervix [3-7].