Monocyclic aromatics, methyl-[beta]-orcinolcarboxylate, and methylorsellinate exhibited 4-5-fold higher activity than acarbose , whereas depsidone salazinic acid, depside sekikaic acid, and dibenzofuran usnic acid
showed compatible [IC.sub.50] value as compared to the standard acarbose .
has been one of the most studied lichen compound for its pharmacotoxicological actions, including its antioxidant potential.
It was reported that usnic acid
is one of the active ingredients of the supplement Lipokinetix[R], causing hepatocellular damage .
Except for usnic acid
, no cytotoxic effects were observed for the two depsides (atranorin and perlatolic acid) and the alkyl depsidone (physodic acid).
Antiviral, antiprotozoal, antiproliferative, analgesic, anti-inflammatory and antipyretic activities of usnic acid
known as secondary metabolite have been reviewed.
Although the cytotoxicity of usnic acid
have been extensively reviewed (Muller, 2001; Cocchietto et al., 2002; Ingolfsdottir, 2002) there is no data regarding the effects of usnic acid
The TLC shows the presence of Usnic acid
and sekikaic acid aggregates.
By HPTLC and HPLC analyses were detected: placodiolic acid (major), atranorin (minor), usnic acid
([+ or -] trace, present only in BCRU 01063), haematommone (trace).
In late March, researchers found the high levels of usnic acid
found in tumbleweed shield lichen (lichens are part fungus, part algae) was the cause of the deaths.
is effective against streptococcus, staphylococcus, and bacteria that causes pneumonia.
Some of the supplements in question include kava, usnic acid
and bitter orange (citrus aurantium).