usnic acid


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usnic acid

(ŭs′nĭk)
n.
An antibacterial substance, C18H16O7, obtained from lichens of several genera, including Usnea.
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References in periodicals archive ?
Cellular Mechanisms of the Anticancer Effects of the Lichen Compound Usnic Acid. Planta Medica 76 (10): 969-974.
Monocyclic aromatics, methyl-[beta]-orcinolcarboxylate, and methylorsellinate exhibited 4-5-fold higher activity than acarbose [16], whereas depsidone salazinic acid, depside sekikaic acid, and dibenzofuran usnic acid showed compatible [IC.sub.50] value as compared to the standard acarbose [36].
Usnic acid has been one of the most studied lichen compound for its pharmacotoxicological actions, including its antioxidant potential.
It was reported that usnic acid is one of the active ingredients of the supplement Lipokinetix[R], causing hepatocellular damage [12].
Except for usnic acid, no cytotoxic effects were observed for the two depsides (atranorin and perlatolic acid) and the alkyl depsidone (physodic acid).
Antiviral, antiprotozoal, antiproliferative, analgesic, anti-inflammatory and antipyretic activities of usnic acid known as secondary metabolite have been reviewed.
Although the cytotoxicity of usnic acid have been extensively reviewed (Muller, 2001; Cocchietto et al., 2002; Ingolfsdottir, 2002) there is no data regarding the effects of usnic acid on microtubules.
By HPTLC and HPLC analyses were detected: placodiolic acid (major), atranorin (minor), usnic acid ([+ or -] trace, present only in BCRU 01063), haematommone (trace).
In late March, researchers found the high levels of usnic acid found in tumbleweed shield lichen (lichens are part fungus, part algae) was the cause of the deaths.
Usnic acid is effective against streptococcus, staphylococcus, and bacteria that causes pneumonia.
Some of the supplements in question include kava, usnic acid and bitter orange (citrus aurantium).