uroporphyrinogen
(redirected from uroporphyrinogen I synthetase)uroporphyrinogen
[u″ro-por″fĭ-rin´o-jen]a porphyrinogen formed from porphobilinogen; it is a precursor of uroporphyrin and coproporphyrinogen.
por·phy·rin·o·gens
(pōr'fi-rin'ō-jenz),Intermediates in the biosynthesis of heme, as follows: four porphobilinogens condense to form uroporphyrinogens I and III (giving rise to side products uroporphyrins I and III) that are decarboxylated to form coproporphyrinogens I and III (giving rise to side products coproporphyrins I and III); coproporphyrinogen III is oxidized to protoporphyrinogen III (IX), which is then oxidized to form protoporphyrin III (IX) (this last intermediate adds ferrous iron to yield heme); certain porphyrinogens are elevated in certain porphyrias.
uroporphyrinogen
/uro·por·phy·rin·o·gen/ (-por″fĭ-rin´o-jen) a porphyrinogen formed from porphobilinogen; it is a precursor of uroporphyrin and coproporphyrinogen.por·phy·rin·o·gens
(pōr'fir-in'ō-jenz)Intermediates in the biosynthesis of heme; certain porphyrinogens are elevated in certain porphyrias.
uroporphyrinogen
a precursor of uroporphyrin and coproporphyrinogen.
uroporphyrinogen III
first tetrapyrrole compound in the pathway of porphyrin synthesis from combination of four porphobilinogen compounds via the action of uroporphyrinogen I synthetase and uroporphyrinogen III cosynthetase.
uroporphyrinogen III cosynthetase
an enzyme involved in the synthesis of uroporphyrinogen.
uroporphyrinogen isomerase
see uroporphyrinogen III cosynthetase (above).
uroporphyrinogen I synthetase
an enzyme involved in the synthesis of uroporphyrinogen.