urobilinogen


Also found in: Dictionary, Thesaurus, Encyclopedia, Wikipedia.

urobilinogen

 [u″ro-bi-lin´o-jen]
a colorless compound formed in the intestines by the reduction of bilirubin; the urobilinogen in the urine normally represents about 1 per cent of the bilirubin produced in the body by the breakdown of hemoglobin. Increased amounts in the urine indicate excessive bilirubin in the blood. Determination of the amount of urobilinogen excreted in a given period makes it possible to evaluate certain types of hemolytic anemia and also is of help in diagnosing liver dysfunction.



Laboratory tests for urobilinogen require collection of urine for a 24-hour period or for a 2-hour period. The 2-hour afternoon collection of urine is most commonly used because it is more convenient and also because it has been found that the excretion of urobilinogen reaches its maximum in the period from midafternoon to late evening. There is no special preparation of the patient for these tests. The exact time period in which the urine has been collected must be noted. The specimen should be taken to the laboratory immediately, since bacteria that may be present in the urine can oxidize urobilinogen and change it to urobilin.

u·ro·bi·lin·o·gen

(yūr'ō-bī-lin'ō-jen),
Precursor of urobilin.

urobilinogen

/uro·bi·lino·gen/ (-bi-lin´o-jen) a colorless compound formed in the intestines by reduction of bilirubin.

urobilinogen

[yoo͡r′əbīlin′əjən]
a colorless compound formed in the intestine after the breakdown of bilirubin by bacteria. Some of this substance is excreted in feces, and some is resorbed and excreted again in bile or urine. See also urobilin.

u·ro·bi·lin·o·gen

(yūr'ō-bi-lin'ō-jen)
Precursor of urobilin.

urobilinogen

A pigment formed from BILIRUBIN in the intestine by bacterial action that is absorbed into the bloodstream and excreted in the urine. Excess is found in the urine in HAEMOLYTIC ANAEMIA and certain liver disorders. None is found in complete obstruction to the the outflow of bile from the liver.

urobilinogen

a colorless compound formed in the intestines by the reduction of bilirubin. Small amounts of the bilirubin produced in the body by the breakdown of hemoglobin are excreted in the urine as urobilinogen. Increased amounts of urobilinogen in the urine indicate an excessive amount of bilirubin in the blood. Determination of the amount of urobilinogen excreted in a given period makes it possible to evaluate certain types of hemolytic anemia and also is of help in diagnosing liver dysfunction such as hepatocellular damage.

fecal urobilinogen
a group of urobilinoid substances which react with Ehrlich's reagent. Presence indicates an open bile duct and a functional enterohepatic circulation of bile pigments.
References in periodicals archive ?
Increased reabsorption of bilirubin from the gut, due to lack of conversion to urobilinogen by gut bacteria.
This study has documented significantly higher urinary bilirubin and urobilinogen in malarial patients in comparison to healthy controls.
The qualitative protein, qualitative glucose, urobilinogen, bilirubin, ketone body, nitrite, leukocyte esterase, and occult blood tests results were negative for specimens from all groups.
For non-binary responses analytes (responses that are numeric), the greatest percentage of disagreement between the unstressed and stressed strips for exact block output was observed with glucose, ketone, leukocyte, and urobilinogen tests on both Clarity and Roche Strips.
These test strips are the same as used in the Miditron but are supplied in a cassette holding 400 test strips for leukocyte esterase, nitrite, protein, glucose, ketones, urobilinogen, bilirubin, hemoglobin/myoglobin, and pH.
The DiaScreen 50 Urine Chemistry Analyzer tests urine specimens for the presence of leukocytes, specific gravity, urobilinogen, glucose, ketone, bilirubin, protein, nitrite, blood, and [sub.
Dipstick urinalysis (protein, glucose, occult blood, urobilinogen, bilirubin, ketones, pH, and specific gravity) was performed with Ames reagent strips (Multistix SGL; Miles-Sankyo Co.
2005 on the minimum requirements for ensuring health and safety at work with visual display and view the service Occupational Medicine, type of prophylactic examinations in District Prosecutor Slivnitsa is defined as follows: Urine with politest of indicators - pH, specific gravity, albumin / protein / sugar, acetone, bilirubin, urobilinogen, blood tests - biochemical blood test for cholesterol, triglycerides (lipid status) and blood sugar; neurologist - diagnosis and prevention of central and peripheral nervous system; ophthalmologist - overview and visual acuity and refraction, internist - history, status, blood pressure, ECG reading, reading laboratory tests.
Urine nitrites can be falsely elevated due to contamination, air exposure, or phenazopyridine, and can be falsely negative due to elevated specific gravity, elevated urobilinogen levels, nitrate reductase-negative bacteria, PH < 6.
Substances such as urobilinogen, phenothiazines, indoles, and methlydopa, which are known to cause false-positive results with colorimetric methods (20, 21), do not interfere with the LC-MS/MS method, which quantifies based on the monitoring of a specific fragment ion of PBG in ratio to a labeled PBG internal standard.
It is generally stable for six hours to eight hours when refrigerated--although both bilirubin and urobilinogen are especially susceptible to exposure to light.
Test strips are widely used to estimate pH and to detect nitrites, protein, glucose, ketones, urobilinogen, bilirubin, leukocytes, and hemoglobin in urine.