uridine diphosphate


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uridine

 [u´rĭ-dēn]
a ribonucleoside containing uracil.
uridine diphosphate (UDP) a nucleotide that participates in glycogen metabolism and in some processes of nucleic acid synthesis.

uridine diphosphate

A uridine-containing nucleotide important in certain metabolic reactions, in which it transports sugars such as glucose and galactose.
See also: uridine
References in periodicals archive ?
[4] Nonstandard abbreviations: GALK, galactokinase; GALT, galactose-1-phosphate uridylyltransferase; GALE, uridinediphosphate galactose4'-epimerase; UDPGal, uridine diphosphate galactose; UDPGlc, uridine diphosphate glucose; EBV, Epstein-Barr virus; LC-MS/MS, liquid chromatography-tandem mass spectrometry; IRB, Institutional Review Board; Hb, hemoglobin.
Multiple forms and intracellular localization of uridine diphosphate glucose pyrophosphorylase in Avena sativa.
Six calibrators were prepared, which consisted of aqueous solutions containing the internal standard (IS) [[sup.13][C.sub.6]]-Glu-1-P at a constant concentration of 2.0 [micro]mol/L and uridine diphosphate galactose (UDPGal) concentrations of 12.5, 2.5, 0.5, 0.1, 0.02, and 0.004 [micro]mol/L.
It was incubated for 10 min at 37[degrees]C before being added to the GALT assay to destroy endogenous [NAD.sup.+] and thus inactivate uridine diphosphate 4'-epimerase (19).
Role of uridine diphosphate glucuronosyltransferase isoform 1A1 in the glucuronidation of its active metabolite (SN-38) in human liver microsomes.
TATA-box mutant in the promoter of the uridine diphosphate glucuronosyltransferase gene in Italian patients with Gilbert's syndrome.
Anti-microsomal antibodies targeting P450IA2 and P450IIIAl isoenzymes have also been reported in idiosyncratic liver injuries associated with dihydralazine and aromatic anticonvulsants, as well as anti-LKM3 antibodies directed against uridine diphosphate glucuronyltransferase (UDPGT) enzymes [24-26].
The most common type of phase II reaction is glucuronidation, where glucuronic acid is transferred from uridine diphosphate glucuronic acid (UDPGA) to a drug or phase I metabolite by the enzyme UDPGT [7].

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