urethral bulking agent

urethral bulking agent

Urogynecology An injectable hydrogel composed of a biocompatible recombinant protein polymer used to bulk tissue about the intrinsic sphincter to provide complete closure and urinary control for ♀ with incontinence due to intrinsic sphincter deficiency. See Urinary incontinence.
References in periodicals archive ?
The Macroplastique Implants is an injectable urethral bulking agent to treat adult female stress urinary incontinence primarily due to intrinsic sphincter deficiency.
Injectable Teflon was widely used as a urethral bulking agent in the 1950s and 1960s and was effective, but it has been largely abandoned because of fear that the Teflon would migrate to other tissues, as well as other safety issues.
That leaves two materials--collagen and microcarbon beads--that have been approved by the Food and Drug Administration as urethral bulking agents.
-- The urethral bulking agent Uryx improved stress urinary incontinence comparably or better than Contigen 12 months after treatment in a multicenter study presented at the annual meeting of the American Urogynecologic Society.
Use of the urethral bulking agent Tegress is strongly associated with urethral erosions and urinary fistulas.
Chapter 08 -- Global Female Stress Urinary Incontinence Treatment Devices Market Analysis 2014 - 2018 & Forecast 2019 - 2029, By Product Type Based on the product type, the female stress urinary incontinence treatment devices market is segmented into sling systems, artificial urinary sphincter (AUS), and injectable urethral bulking agents. Sling systems are further sub-segmented into mid-urethral sling systems and sub-urethral sling systems.
Minimally invasive treatment, such as the injection of urethral bulking agents, may also be used.
(2,3) SUI treatment options, beginning from least to most invasive, include pelvic floor exercises, biofeedback and/or physical therapy, continence devices, off-label use of medications, urethral bulking agents, and surgical correction with slings.
* Urethral bulking agents. Food and Drug Administration-approved urethral bulking agents include collagen (Conti-gen), calcium hydroxylapatite (Coaptite), and carbon bead particles (Durasphere).
Targeted products include urethral bulking agents for the treatment of stress urinary incontinence, dermal augmentation products for cosmetic and reconstructive surgery, surgical adhesives and sealants, scaffolds for wound healing and tissue engineering, and depots for local drug delivery.
(1) Injectable urethral bulking agents fall along this spectrum and offer a less invasive treatment option for selected women with SUI.
(1-4) Treatment includes observation, pelvic floor training, urethral bulking agents, male urethral sling (MUS), and artificial urinary sphincter (AUS).