urea clearance

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Related to urea clearance: urea clearance test

u·re·a clear·ance

the volume of plasma (or blood) that would be completely cleared of urea by 1 minute's excretion of urine; originally calculated as urine flow multiplied by urine urea concentration divided by concentration of urea in whole blood rather than plasma, representing blood urea clearance rather than plasma urea clearance.

u·rea clear·ance

(yūr-ē'ă klēr'ăns)
C with a subscript indicating the substance removed; volume of plasma (or blood) that would be completely cleared of urea by 1 minute's excretion of urine.


the act of clearing; it is a primary pharmacokinetic parameter which describes irreversible removal of a drug from the body by all processes and is made up of renal clearance and metabolic clearance.

blood-urea clearance
the volume of the blood cleared of urea per minute by renal elimination.
Bromsulphalein clearance
see sulfobromophthalein clearance test.
creatinine clearance
inulin clearance
see inulin clearance.
clearance time
the time required for a drug to be eliminated after administration. Eliminated means to the point where it can no longer be detected. Of most importance in avoiding drug residues in food animals and charges of doping in sports animals.
urea clearance
blood-urea clearance.
References in periodicals archive ?
In conclusion, the findings of the current study show that the prescribed intradialytic aerobic exercise program resulted in significant improvement in urea clearance.
The measured urea clearances (K) for 2400 ml and 3000 ml/h substitution fluid flow corresponded well to the predicted urea and creatinine clearances of 30 ml/min and 37.
Determining the impact of blood flow rates on urea clearance is essential for clinicians to enact evidence-informed practice and protect patients from harm.
Their prediction equations 6 and 7 decreased unexplained variance from measured GFR by more than one-half when compared with measured creatinine or urea clearance or the Cockcroft-Gault equation, i.
There are two formulas we use in the Southern Alberta Renal Program (SARP) to assess adequacy based on urea clearance.
The recommended urea clearance target should be at least 2L/week, and the creatinine clearance target should be at least 60L/week in high and high average peritoneal transporters; and 50L/week in low average and low peritoneal transporters (Baxter HealthCare Corporation, 2006).