urate

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Related to urate calculi: Urate crystals, uric acid calculi

urate

 [u´rāt]
a salt of uric acid.

u·rate

(yū'rāt),
A salt of uric acid.

urate

(yūr'āt)
A salt of uric acid.

urate

A salt of uric acid.
Urateclick for a larger image
Fig. 311 Urate . Molecular structure.

urate (uric acid)

an end product of PURINE degradation in humans, which is excreted in the urine. Purine degradation proceeds further in other mammals so that urate is oxidized and ALLANTOIN, for example, is excreted. In land animals such as reptiles and birds, urate is excreted as the final product of nitrogen metabolism, instead of UREA, in order to conserve water. Purines are synthesized using their excess amino nitrogen and then degraded to urate. By eliminating nitrogen in this way there is a minimum of water loss and the urate is excreted either as a thick paste or as dry pellets. A high amount of urate in serum can cause gout, a disease that affects the joints and kidneys. Formula: C5H4N4O3.