urate


Also found in: Dictionary, Thesaurus, Encyclopedia, Wikipedia.

urate

 [u´rāt]
a salt of uric acid.

u·rate

(yū'rāt),
A salt of uric acid.

urate

(ūr´āt) any salt or anion of uric acid (q.v.).

urate

[yoo͡r′āt]
any salt of uric acid, such as sodium urate. Urates are found in urine, blood, and tophi or calcareous deposits in tissues. They also may be deposited as crystals in joints. See also gout, uric acid.

urate

(yūr'āt)
A salt of uric acid.

urate

A salt of uric acid.
Urateclick for a larger image
Fig. 311 Urate . Molecular structure.

urate (uric acid)

an end product of PURINE degradation in humans, which is excreted in the urine. Purine degradation proceeds further in other mammals so that urate is oxidized and ALLANTOIN, for example, is excreted. In land animals such as reptiles and birds, urate is excreted as the final product of nitrogen metabolism, instead of UREA, in order to conserve water. Purines are synthesized using their excess amino nitrogen and then degraded to urate. By eliminating nitrogen in this way there is a minimum of water loss and the urate is excreted either as a thick paste or as dry pellets. A high amount of urate in serum can cause gout, a disease that affects the joints and kidneys. Formula: C5H4N4O3.

urate

a salt of uric acid. Accumulates in tissues in large quantities in chickens fed excessive amounts of protein. See also visceral gout.

urate calculi
see urate uroliths.
References in periodicals archive ?
Studies of urate crystallisation in relation to gout.
Medicines for gout are aimed at reducing pain and swelling in the affected joints, increasing the kidneys' ability to excrete urate and decreasing the body's production of uric acid.
Only 6 to 8 percent of all uroliths are urate or purine stones, but their presence in certain breeds is significant.
No fecal material was retrieved from the enema, and the bird did not pass any fecal material overnight, only a small amount of urates.
And the researchers found that the disease progressed more slowly in participants with the highest levels of urate than in people with the lowest levels.
This study has identified urate as a bio-marker for the progression of the disease and suggests a potential new pathway for targeted therapy development.
Urate within aspirated or scraped material is seen as strongly negative, birefringent, needle-shaped crystals under polarized light (figure 1, A) or alcohol-fixed, methylene-blue-stained (figure 1, B).
Results: Plasma urate decreased five hours post-dose to 185 [+ or -] 15 umol/L compared with predose baseline of 214 [+ or -] 13 umol/L (p=0.
In contrast to ethanol and water, consumption of both wine and polyphenolics-stripped wine produced increases in plasma urate concentrations and antioxidant capacity, reaching peak values after 60 min (Fig.
3) Despite the risk of urate precipitation, urine should be refrigerated if analysis is not possible within two hours of collection.
We also indirectly measured the amount of urate that was moved out of the body in urine.
8] In such cases, H&E-stained sections may not detect either CPPD or monosodium urate crystals.