The cytotoxicity of [beta]-lg nanoparticles in Caco-2 cells were determined by measuring the cell survival ratio using flow cytometry prior to cellular uptake study (Figure 3).
The in vitro or in vivo cellular uptake of nanoparticles was investigated by the use of fluorescent-based method (Win and Feng, 2005).
It is believed that the cellular uptake of nanoparticles was affected by various morphological- and physicochemical properties of nanoparticles, such as their size and surface charge (Mansouri et al.
On the other hand, an increase in the cellular uptake of [beta]-lg nanoparticles was observed when [beta]-lg nanoparticles treated at lower heating temperature had higher zeta potential value (surface charge) (Figure 5).
A number of studies have measured an individual's uptake of DBPs from various activities, using biologic markers such as breath samples, blood plasma samples, and urinary excretion rates (Nieuwenhuijsen et al.
Uptake of chloroform was simulated based on information in the published literature about frequency and duration of each activity, amount of water ingested, and measured increases in blood chloroform concentrations.
Therefore, 90 days of chloroform uptake via showering, bathing, ingestion of tap water, and swimming were simulated for each mother and then averaged to give an average daily uptake for all pathways.
Uptake parameters were based only on studies measuring blood chloroform concentrations because these were thought to be the most biologically relevant and informative.
01) in the effect parameter for both the 8and 24-hr uptakes when we compared the data from our study with the combined data from the other two studies.
Correlation of the 24-hour radioiodine uptake of the human thyroid gland with the six- and eight-hour uptakes and the "accumulation gradient.
To establish the dose response in humans for perchlorate inhibition of thyroidal iodide uptake and any short-term effects on thyroid hormones, we gave perchlorate in drinking water at 0.
If sufficient inhibition of iodide uptake occurs, formation of thyroid hormones is depressed.