universal donor


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Related to universal donor: Rh factor, universal recipient

donor

 [do´ner]
1. a person or organism that supplies an organ or tissue to be used in another body, usually either a cadaveric, living related, or living unrelated donor; see transplantation.
2. a substance or compound that contributes part of itself to another substance (acceptor).
Algorithm for organ donation. From McQuillan, 2002.
cadaveric donor an organ or tissue donor who has already died; see cadaveric donor transplantation.
living nonrelated donor living unrelated donor.
living related donor one who is a close blood relative of the recipient; see living related donor transplantation.
living unrelated donor one who is not a close blood relative of the recipient; see living unrelated donor transplantation.
non–heart beating cadaveric donor a donor who has been pronounced dead according to the traditional criteria of lack of any pulse or detectable cardiac activity, but is not yet brain dead (see brain death). There are two types: The controlled donor is a person in a vegetative state who has signed a consent form or otherwise stated his or her wishes before becoming ill. Based on the patient's stated wishes and at the request of the next-of-kin, cannulas are placed into blood vessels for postmortem cooling of organs and the person is removed from life support. Once death has been declared, the organs are rapidly perfused with cold preservative solution and surgically removed. The uncontrolled donor is a person declared dead because of catastrophic injury to the heart, such as a gunshot wound to the heart. Cannulas are placed into blood vessels after death and the organs are perfused and removed. This also requires consent of next-of-kin.
universal donor a person whose blood is type O in the ABO blood group system; such blood is sometimes used in emergency transfusion. Transfusion of blood cells rather than whole blood is preferred.

u·ni·ver·sal do·nor

in blood grouping, a person belonging to group O; that is, one whose erythrocytes do not contain either agglutinogen A or B and are, therefore, not agglutinated by plasma containing either of the ordinary isoagglutinins.

universal donor

n.
A person who has group O blood and is therefore able to serve as a donor to a person of any other blood group in the ABO system.

universal donor

type O, Rh negative red blood cells that may be used for emergency transfusion to any ABO type with minimal risk of incompatibility. Group AB plasma can be transfused to all ABO types. See also blood donor, blood group, transfusion.
A person with blood group O, whose erythrocytes lack A and B antigens and thus do not elicit a haemolytic transfusion reaction when the blood is transfused to a person with blood group A, B, AB or O

universal donor

Transfusion medicine A person with blood group O, whose RBCs lack A and B antigens and thus do not elicit a hemolytic transfusion reaction when the blood is transfused to a person with blood group A, B, AB or O. Cf Universal recipient.

u·ni·ver·sal do·nor

(yū'ni-vĕr'săl dō'nŏr)
In blood grouping, a person belonging to group O, i.e., one whose erythrocytes contain neither agglutinogen A nor B and are Rh negative.

uni·ver·sal do·nor

(yū'ni-vĕr'săl dō'nŏr)
In blood grouping, a person belonging to group O.
References in periodicals archive ?
Particularly, the military needs a constant supply of fresh, universal donor blood for battlefield situations when normal supplies from donors can quickly run out.
president of AIRM, Astellas Institute for Regenerative Medicine, said, 'I am pleased to enter into this collaboration with Universal Cells for a novel cell therapy using their proprietary Universal Donor Cell technology based on gene editing by rAAV (recombinant Adeno-Associated Virus) and cell engineering of pluripotent stem cells.
OTCBB: ACTC) says a new study shows that its proprietary iPSC Platelet technology is potentially capable of producing large-scale quantities of universal donor platelets for transfusion in almost any patient.
Allogeneic cell therapy involves the harvesting of cells from a healthy, universal donor, rather than from the patient being treated.
We currently have less than one day's supply of O-positive and O- negative blood, the universal donor group often used in emergencies,'' said Christine Hobley, donor recruitment representative for Santa Clarita.
Given that the ERC can be produced in large quantities, is a universal donor cell, and already is approved for clinical trials in both the USA and Russia, we are optimistic our collaboration will lead to a viable commercial product for the type 1 diabetes Russian population.
M2 EQUITYBITES-March 22, 2011-China PharmaHub exclusively licenses universal donor red blood cells technology from University of California(C)2011 M2 COMMUNICATIONS http://www.
Donations typically fall off during the holidays, but many regular donors have been sick and unable to give blood, which has left the American Red Cross Los Angeles chapter 500 units short of type O blood, the universal donor type.
Medistem is a pioneer in the development of Endometrial Regenerative Cells (ERC), universal donor adult stem cells that stimulate new blood vessel formation and are capable of generating different tissues including heart, brain, pancreas, liver, bone, cartilage and lung.
Biotechnology company Medistem Inc (PINKSHEETS:MEDS) on Saturday announced that it has begun a collaboration with Chinese conglomerate Shanghai Jia Fu Medical Apparatus Inc in the development of the Endometrial Egenerative Cell (ERC) universal donor stem cell product for the Chinese market.
The company is using its Endometrial Regenerative Cell (ERC) universal donor stem cell product to treat ischemia in legs and hearts.

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