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A protein that mediates the transport of one molecule or ion through a membrane without known coupling to the transport of any other molecule or ion.
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The mitochondrial calcium uniporter selectively matches metabolic output to acute contractile stress in the heart," Cell Reports, vol.
The mitochondrial calcium uniporter matches energetic supply with cardiac workload during stress and modulates permeability transition," Cell Reports, vol.
Rizzuto, "Structure and function of the mitochondrial calcium uniporter complex," Biochimica et Biophysica Acta (BBA)--Molecular Cell Research, vol.
Xia, "Role of mitochondrial calcium uniporter in myocardial hypoxia/reoxygenation induced injury," Chinese Journal of Applied Physiology, vol.
MiR-25 protects cardiomyocytes against oxidative damage by targeting the mitochondrial calcium uniporter," International Journal of Molecular Sciences, vol.
2+] chelator, and Ru360, an inhibitor of calcium uniporter which mediates influx of the ions from the ER directly into mitochondria.
2+] uniporter Ru360, and ROS levels were analyzed 28 hrs after transfection in DHE (b) or [H.
2+] regulator proteins settled in the MAMs like IP3R, and VDAC and the uniporter mitochondrial [Ca.
Integrative genomics identifies MCU as an essential component of the mitochondrial calcium uniporter," Nature, vol.