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1. Not in good physical or mental health.
2. Biology Unable to survive or produce viable offspring in a particular environment.
tr.v. un·fitted, un·fitting, un·fits
To cause to be unsuited or unqualified: "Having run for president ... often unfits a man for lesser or more useful subsequent work" (Garry Wills).
not properly prepared, e.g. physically incapable of performing hard work as in racing, because of lack of training. Said also of food prepared unhygienically.
unfit for human consumption
meat or other food considered by a qualified food inspector to be unsuited for entry into the human food chain because of the presence of disease, immaturity, physical damage, emaciation, edema, contamination by gut contents or unauthorized additives or being meat of another, unauthorized species, or meat that has not undergone approved inspection by health authorities.