SLC45A2

(redirected from underwhite)

SLC45A2

A gene on chromosome 5p13.2 that encodes solute carrier family 45, member 2, which is a melanocyte differentiation antigen thought to transport substances required for melanin biosynthesis. It is expressed in most melanoma cell lines and melanocytes.

Molecular pathology
SLC45A2 mutation causes oculocutaneous albinism type 4.
References in periodicals archive ?
Mutations in the human orthologue of the mouse underwhite gene (uw) underlie a new form of oculocutaneous albinism, OCA4.