understaging

understaging

(ŭn′dĕr-stāj″ing)
Underestimation of the severity of a patient's illness, esp. an illness such as metastatic cancer. It can occur, for example, as a result of errors in pathological evaluation.
References in periodicals archive ?
(53-55) Initially, this phenomenon was attributed to understaging of tumors, based on the assumption that positive lymph nodes are missed in a proportion of stage II tumors when the yield is low.
Timing of the first postnatal ultrasound has been studied in a limited fashion, yet the practice standard has become to avoid doing an US in the first 2 days of life due to a concern of understaging secondary to neonatal oliguria (1, 21).
More recently, some authors suggested a routinary nodal sampling in PanNETs in order to reduce the possibility of tumor understaging rather than to prolong survival itself [83].
Altorki, "POINT: clinical stage IA non-small cell lung cancer determined by computed tomography and positron emission tomography is frequently not pathologic IA non-small cell lung cancer: the problem of understaging," Journal of Thoracic and Cardiovascular Surgery, vol.
Nonetheless, AS has raised several concerns, among them, the clinical understaging and undergrading, and the presence of unfavorable histological findings in certain patients that previously met very low risk criteria.
Indeed, the poor preoperative/intraoperative staging concordance indicates the understaging of our patients.
Systematic cytology at diagnosis could be more accurate to evaluate peritoneal extension in order to avoid understaging and adjust adjuvant locoregional treatment [31].
Additionally, the liver biopsy samples obtained by transjugular biopsy were small, with 6 (26%) suboptimal for grading, likely resulting in understaging and undergrading of fibrosis [32] and potentially attenuating relationships between biopsy parameters and noninvasive markers.
SN detection allows a more detailed and accurate histological analysis, reducing the possibility of understaging lymph node involvement (7,8).
The observation implied that preoperative unfavorable numbers of CTM in peripheral blood might reflect the aggressiveness of tumor or the understaging of PDCA by the current staging modality.
Of the patients who achieved cT0 after NC, 7 (33%) had evidence of residual disease within the resected specimen at PC, which is close to 30% of understaging with TURBT alone reported by our institution's Herr and Scher study [12].
False-negative SLNB results might impair patient outcomes for several reasons since missed nodes might lead to axillary recurrence that is difficult to treat and understaging could affect decisions about systemic and radiation therapy.