ultracentrifuge

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ultracentrifuge

 [ul″trah-sen´trĭ-fūj]
the centrifuge used in ultracentrifugation.

ul·tra·cen·tri·fuge

(ŭl'tră-sen'tri-fyūj),
A high-speed centrifuge (up to 100,000 rpm) by means of which large molecules, for example, of protein or nucleic acids, are caused to sediment at practicable rates; used for determinations of molecular weights, separation of large molecules, criteria of homogeneity of large molecules, conformational studies, etc.

ultracentrifuge

(ŭl′trə-sĕn′trə-fyo͞oj′)
n.
A high-velocity centrifuge used in the separation of colloidal or submicroscopic particles.

ul′tra·cen·trif′u·gal (-trĭf′yə-gəl, -trĭf′ə-gəl) adj.
ul′tra·cen·trif′u·gal·ly adv.
ul′tra·cen′tri·fu·ga′tion (-fyo͝o-gā′shən) n.

ultracentrifuge

[ul′trəsen′trifyo̅o̅j]
Etymology: L, ultra, beyond; Gk, kentron, center; L, fugere, to flee
a high-speed centrifuge with a rotation rate fast enough to produce sedimentation of protein and viruses, even in blood plasma. Use of an attached microscope may make it possible to see the sediment.

ul·tra·cen·tri·fuge

(ŭl'tră-sen'tri-fyūj)
A high-speed centrifuge by means of which large molecules (e.g., of protein or nucleic acids) are caused to sediment at practicable rates.

ultracentrifuge

A device for rotating small containers at extremely high speed so as to expose the liquid contents to powerful centrifugal force, of the order of 100,000 g. Ultracentrifuges are used to separate particles of molecular size and determine molecular weights.

ultracentrifuge

a machine capable of spinning a rotor at speeds of up to 50 000 revolutions per minute, producing up to 500 000 g forces. The high speeds enable the separation of tiny particles, which are identified by the rate at which they move down the centrifuge tube. The unit of rate is called the Svedberg (S), after the inventor of the ultracentrifuge. Thus RIBOSOMES are found to consist of two subunits after ultracentrifugation, called 30S and 50S. See also DENSITY-GRADIENT CENTRIFUGATION, DIFFERENTIAL CENTRIFUGATION, MICROSOMAL FRACTION.

ul·tra·cen·tri·fuge

(ŭl'tră-sen'tri-fyūzh)
A high-speed centrifuge by means of which large molecules sediment at practicable rates.

ultracentrifuge,

n a high-speed centrifuge with a rotation rate fast enough to produce sedimentation of viruses, even in blood plasma. Many kinds of biochemical analyses use ultracentrifuge, including such analyses as the measurement and separation of some proteins and viruses.

ultracentrifuge

the centrifuge used in ultracentrifugation.
References in periodicals archive ?
Use of plasma recovered from ultracentrifuged microhematocrit tubes has been anecdotally implicated as causing deleterious changes to biochemical values, specifically from hemolysis.
The supernatant was finally ultracentrifuged (110,000 x g for 1 h at 4[degrees]C), and viruses were resuspended in 0.
To examine whether the time-dependent increase in serum sCD40L concentrations was attributable to release of platelet microparticles producing membrane sCD40L, we either filtered or ultracentrifuged specimens before repeat testing.
The results of the Student-Newman-Keuls test also indicated that there was no significant difference between the filtered and the ultracentrifuged groups but that each of them was significantly different from the group that did not undergo additional filtration or ultracentrifugation.
22 [micro]m-filtered and ultracentrifuged samples compared with paired unfiltered samples, indicating that an important fraction of plasma RNA is particle associated.
22 [micro]m filter, and ultracentrifuged plasma (Friedman test, P <0.
The samples were ultracentrifuged (24 h with the SW 28 rotor or 19 h with the 45 Ti rotor) at 20 [degrees]C.
Precooled rotors were ultracentrifuged in either a Beckman L7-55 or a L8-55 ultracentrifuge that had been precooled to 10[degrees]C.