ultracentrifuge

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ultracentrifuge

 [ul″trah-sen´trĭ-fūj]
the centrifuge used in ultracentrifugation.

ul·tra·cen·tri·fuge

(ŭl'tră-sen'tri-fyūj),
A high-speed centrifuge (up to 100,000 rpm) by means of which large molecules, for example, of protein or nucleic acids, are caused to sediment at practicable rates; used for determinations of molecular weights, separation of large molecules, criteria of homogeneity of large molecules, conformational studies, etc.

ultracentrifuge

(ŭl′trə-sĕn′trə-fyo͞oj′)
n.
A high-velocity centrifuge used in the separation of colloidal or submicroscopic particles.

ul′tra·cen·trif′u·gal (-trĭf′yə-gəl, -trĭf′ə-gəl) adj.
ul′tra·cen·trif′u·gal·ly adv.
ul′tra·cen′tri·fu·ga′tion (-fyo͝o-gā′shən) n.

ultracentrifuge

[ul′trəsen′trifyo̅o̅j]
Etymology: L, ultra, beyond; Gk, kentron, center; L, fugere, to flee
a high-speed centrifuge with a rotation rate fast enough to produce sedimentation of protein and viruses, even in blood plasma. Use of an attached microscope may make it possible to see the sediment.

ul·tra·cen·tri·fuge

(ŭl'tră-sen'tri-fyūj)
A high-speed centrifuge by means of which large molecules (e.g., of protein or nucleic acids) are caused to sediment at practicable rates.

ultracentrifuge

A device for rotating small containers at extremely high speed so as to expose the liquid contents to powerful centrifugal force, of the order of 100,000 g. Ultracentrifuges are used to separate particles of molecular size and determine molecular weights.

ultracentrifuge

a machine capable of spinning a rotor at speeds of up to 50 000 revolutions per minute, producing up to 500 000 g forces. The high speeds enable the separation of tiny particles, which are identified by the rate at which they move down the centrifuge tube. The unit of rate is called the Svedberg (S), after the inventor of the ultracentrifuge. Thus RIBOSOMES are found to consist of two subunits after ultracentrifugation, called 30S and 50S. See also DENSITY-GRADIENT CENTRIFUGATION, DIFFERENTIAL CENTRIFUGATION, MICROSOMAL FRACTION.

ul·tra·cen·tri·fuge

(ŭl'tră-sen'tri-fyūzh)
A high-speed centrifuge by means of which large molecules sediment at practicable rates.

ultracentrifuge,

n a high-speed centrifuge with a rotation rate fast enough to produce sedimentation of viruses, even in blood plasma. Many kinds of biochemical analyses use ultracentrifuge, including such analyses as the measurement and separation of some proteins and viruses.

ultracentrifuge

the centrifuge used in ultracentrifugation.
References in periodicals archive ?
Centrifuging blood and harvesting the plasma from the ultracentrifuged microhematocrit tubes appears to be an appropriate means of obtaining sufficient sample volumes to perform plasma biochemical testing on patients as small as 50 g.
To examine whether the time-dependent increase in serum sCD40L concentrations was attributable to release of platelet microparticles producing membrane sCD40L, we either filtered or ultracentrifuged specimens before repeat testing.
Compared with plasma with no additional treatment, the analysis revealed a significant reduction in the mitochondrial DNA concentration in both the filtered and ultracentrifuged groups.
Three serum samples with albumin concentrations 650 [micro]mol/L were ultracentrifuged at 141 000g for 24 h or at 230 000g for 19 h.
Precooled rotors were ultracentrifuged in either a Beckman L7-55 or a L8-55 ultracentrifuge that had been precooled to 10[degrees]C.
Pooled plasma (1 mL) was overlayed with 2 mL of a saline solution (9 g/L NaCI) and ultracentrifuged in a 100.
The hypertriglyceridemic sera were further ultracentrifuged on a Beckman (Fullerton, CA) Airfuge at 122 000g for 10 min to obtain nonlipemic sera.
However, apo B concentrations in the ultracentrifuged sample tended to be higher than those measured in the immunoseparated filtrate, especially at mean LDL-apo B concentrations >~1.