ubiquinone


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coenzyme

 [ko-en´zīm]
an organic molecule, usually containing phosphorus and some vitamins, sometimes separable from the enzyme protein; a coenzyme and an apoenzyme must unite in order to function (as a holoenzyme).
coenzyme A a coenzyme essential for carbohydrate and fat metabolism; among its constituents are pantothenic acid and a terminal SH group, which forms linkages with various acids, e.g., acetic acid (acetyl CoA) and fatty acids (acyl CoA); abbreviated CoA.
coenzyme Q any of a group of related quinones occurring in the lipid fraction of mitochondria and serving, along with the cytochromes, as an intermediate in electron transport; they are similar in structure and function to vitamin K1.

u·bi·qui·none

(ū'bi-kwī'nōn, ū-bik'wi-nōn),
A 2,3-dimethoxy-5-methyl-1,4-benzoquinone with a multiprenyl side chain; a mobile component of electron transport.
See also: coenzyme Q.

ubiquinone

/ubi·qui·none/ (Q) (Q10) (u″bĭ-kwĭ-nōn´) a quinone derivative with an unsaturated branched hydrocarbon side chain occurring in the lipid core of inner mitochondrial membranes and functioning in the electron transport chain. In naturopathic practice it is used for a wide variety of indications; also used as a dietary supplement for its antioxidant properties.

ubiquinone

(yo͞o′bĭ-kwĭ-nōn′, -kwĭn′ōn′)
n.
A quinone compound that serves as an electron carrier between flavoproteins and in cellular respiration.

ubiquinone

[yo̅o̅bik′winōn]
a naturally occurring organic compound found in the lipid core of mitochondrial membranes. It functions as a carrier in the electron transport chain that produces energy. Formerly called coenzyme Q. 2. an herbal supplement used in the treatment of cardiac as well as several other chronic and hereditary diseases. The safety and/or effectiveness of this supplement has not been established by the FDA.

coenzyme Q10

A factor present in mitochondria which extracts energy from foods. It has acquired a reputation among fringe nutritionists as being effective in detoxifying patients with an overdose of environmental pollutants; it is also claimed to be beneficial in treating hypertension, obesity, periodontal disease, preventing cancer, increasing longevity and revitalising the immune system.

u·bi·qui·none

(yū'bi-kwi'nōn)
A 2,3-dimethoxy-5-methyl-1,4-benzoquinone with a multiprenyl side chain; a mobile component of electron transport.
See also: coenzyme Q

ubiquinone

or

coenzyme Q

a type of QUINONE that can be reversibly reduced. It functions as an electron carrier in ELECTRON TRANSPORT SYSTEMS.

ubiquinone

coenzyme Q; component of the electrontransfer chain of oxidative phosphorylation.
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References in periodicals archive ?
Interactions of mitochondria-targeted and untargeted ubiquinones with the mitochondrial respiratory chain and reactive oxygen species.
MitoQ[R]: A Highly Bioavailable, Mitochondria-Targeted Form of Coenzyme Q10
2]S) to persulfide (R-SSH) and transfers two electrons to the ubiquinone pool, as described by Theissen and Martin (2008).
CRUSTACEAN BIOENERGETICS: MITOCHONDRIAL ADAPTIVE MOLECULAR RESPONSES TO FACE ENVIRONMENTAL CHALLENGES
Specifically, it has been demonstrated that other intermediate metabolites alongside IPP contribute to the control of ubiquinone biosynthesis (36).
Inhibition of coenzyme Qs accumulation in engineered Escherichia coli by high concentration of farnesyl diphosphate
The kinetics of the redox reactions of ubiquinone related to the electron-transport activity in the respiratory chain.
Mitochondrial coenzyme Q10 determination by isotope-dilution liquid chromatography-tandem mass spectrometry
Patients on statins have low ubiquinone levels, and coenzyme Q adds it back.
Lower statin dose and add ubiquinone for myalgias
Discuss with the patient whether they want to consider adding ubiquinone (coenzyme Q10) to statin therapy, One positive study suggesting that coenzyme Q10 may reduce statin-related myalgia has been followed by several negative studies.
Titrate statin dose, try ubiquinone for myalgias
Coenzyme Q10 (CoQ10), also known as ubiquinone, is located primarily in mitochondria and is present in most cells.
Coenzyme Q10--a therapeutic agent
3) A possible mechanism to explain this potentially untoward result is the effect of statins in reducing the concentration of ubiquinone, also known as coenzyme Q-10 (CoQ 10), [beta]-carotene and vitamin E, resulting in a deficiency or depletion of these nutrients.
Effects of statin drugs on atherosclerosis and cardiovascular disease due to reductase inhibition and nutrient depletions
13]C]-labeled acetate, a precursor of the MVA pathway, was not incorporated into ubiquinone of Escherichia coli (7) or into a sesquiterpene pentalenolactone, which had been produced by Streptomyces chromofuscus (H.
Two distinct pathways for essential metabolic precursors for isoprenoid biosynthesis
Defects of electron transfer flavoprotein and electron transfer falvoprotein ubiquinone oxidoreductase: glutaric acidemia type II.
Estudio de pacientes con aciduria glutarica tipo II, mediante la incubacion de fibroblastos con acidos palmitico y miristico tritiados
It should be understood by all interested parties that the production processes of each company involved in the manufacture of Ubiquinone are independent of each other and the remarks and documentation provided by ZMC and ZMC-USA in the 340 patent litigation regarding non-infringement by its process are not inclusive of any other manufacturer of Ubiquinone.
ZMC Responds to Xiamen Kingdomway IPO
The causative mutations in HIDS are located in the gene encoding MVK, an enzyme in the isoprenoid metabolism, the end-products of which include cholesterol, and ubiquinone.
An adolescent with hyperimmunoglobulinemia D and periodic fever syndrome responding to simvastatin treatment / Simvastatin tedavisine yanitli hiperimmunoglobulin D ve periyodik ates sendromlu bir adolesan

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