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an antibiotic isolated from the soil bacillus Bacillus brevis, consisting principally of two polypeptides, of which the major one is tyrocidine and the other is gramicidin. It is effective against many gram-positive bacteria, and is applied topically in pyodermic, ocular, and other localized infections.
An antibacterial mixture obtained from peptone cultures of Bacillus brevis; bactericidal and bacteriostatic, and active against gram-positive bacteria. It yields the crystalline antibacterial agents gramicidin and tyrocidin; the gramicidin component is a polypeptide containing l-tryptophan, d-leucine, d-valine, l-valine, l-alanine, glycine, and an aminoethanol; the tyrocidin component is a cyclopolypeptide containing tyrosine, ornithine, and several other amino acids.
A gray-brown mixture consisting mainly of tryocidine and gramicidin, used as a topical antibiotic in treating infections caused by gram-positive bacteria.
tyrothricinAn antibiotic obtained from the soil bacterium Bacillus brevis and used by local application to treat GRAM POSITIVE infections and mouth and throat infections. It is too toxic for systemic use. It is formulated with BENZOCAINE as lozenges under the brand name Tyrozets.
a mixture of tyrocidins and gramicidins used for topical or intramammary application.