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Related to tyrosinase: tyrosine
mon·o·phe·nol mon·o·ox·y·gen·ase(mon-ō-fē'nol mon'ō-oksĭ-jen-ās'),
1. A copper-containing oxidoreductase that catalyzes the oxidation of o-diphenols to o-quinones by O2, with the incorporation of one of the two oxygen atoms in the product; it also catalyzes the oxidation of monophenols, such as l-tyrosine, to dihydroxy-l-phenylalanine (dopa), a precursor of melanin and epinephrine (catecholamines), and can act as a catechol oxidase; a deficiency of this enzyme is observed in several forms of albinism. Synonym(s): cresolase, monophenol oxidase, tyrosinase
2. Synonym(s): laccase
A copper-containing enzyme of plant and animal tissues that catalyzes the production of melanin and other pigments from tyrosine by oxidation, as in the blackening of a peeled or sliced potato exposed to air.
tyrosinase(1) Catechol oxidase, EC 220.127.116.11.
(2) Monophenol monooxygenase, EC 18.104.22.168.
tyrosinaseA copper-containing enzyme that occurs in melanocytes and catalyses the production of MELANIN from TYROSINE. Also known as monophenol mono-oxygenase.
An enzyme in a pigment cell which helps change tyrosine to DOPA during the process of making melanin.
Mentioned in: Albinism
an enzyme important in the production of melanin from tyrosine. Deficiency has been reported in Chow Chows where it is transient and is associated with hypopigmentation of the oral mucosa and hair.