tyrosinase


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Related to tyrosinase: tyrosine

mon·o·phe·nol mon·o·ox·y·gen·ase

(mon-ō-fē'nol mon'ō-oksĭ-jen-ās'),
1. A copper-containing oxidoreductase that catalyzes the oxidation of o-diphenols to o-quinones by O2, with the incorporation of one of the two oxygen atoms in the product; it also catalyzes the oxidation of monophenols, such as l-tyrosine, to dihydroxy-l-phenylalanine (dopa), a precursor of melanin and epinephrine (catecholamines), and can act as a catechol oxidase; a deficiency of this enzyme is observed in several forms of albinism. Synonym(s): cresolase, monophenol oxidase, tyrosinase
2. Synonym(s): laccase

tyrosinase

(tī-rŏs′ə-nās′, -nāz′)
n.
A copper-containing enzyme of plant and animal tissues that catalyzes the production of melanin and other pigments from tyrosine by oxidation, as in the blackening of a peeled or sliced potato exposed to air.

tyrosinase

(1) Catechol oxidase, EC 1.10.3.1. 
(2) Monophenol monooxygenase, EC 1.14.18.1.

tyrosinase

A copper-containing enzyme that occurs in melanocytes and catalyses the production of MELANIN from TYROSINE. Also known as monophenol mono-oxygenase.

Tyrosinase

An enzyme in a pigment cell which helps change tyrosine to DOPA during the process of making melanin.
Mentioned in: Albinism
References in periodicals archive ?
Isolation and characterization of a chicken tyrosinase cDNA.
Based on our results, we conclude that VZ-EO is able to suppress the [alpha]-MSH-induced melanogenesis through tyrosinase inactivation and the simultaneous suppression of oxidative stress in B16 melanoma cells.
Tyrosinase is diverse in terms of its structural properties, tissue distribution, and cellular location as no common tyrosinase protein structure occurs across all species [34, 35].
In addition, thymohydroquinone was found to display higher tyrosinase inhibitory activity (68.82% inhibition at 120 [micro]g/ml) compared to TQ (8.24% inhibition at 166.67 [micro]g/ml) (Lee et al 2011).
As shown in Figure 2C, the tyrosinase inhibitory activity of polysaccharides (0.1 ~1 mg/mL) presented a dose-dependent relationship.
This study presented the potential AChE, tyrosinase, [alpha]-glucosidase inhibitory effects, total phenolic, total flavonoid contents, the antioxidant effects, and prevention of oxidative DNA damage of leaf, stem bark and fruit of various extracts (L1-8, B1-8 and F1-8) from C.
It inhibits tyrosinase and has anti-inflammatory features.
Tyrosinase (MW 128 kDa) from Agaricus bisporus, kojic acid ([greater than or equal to]98%), and L-tyrosine were purchased from Sigma-Aldrich (St.
Before constructing the Lineweaver-Burk plot, the effect of the proso millet extract concentration on tyrosinase activity was determined.
The importance of tyrosinase in pigmentation and exoskeleton formation has been demonstrated, suggesting that compounds capable of inhibiting this enzyme could find utility in skin whitening, pest control, and food conservation applications [33-34].
OCA type 1 (OCA1) is the most severe and common form of OCA, and is caused by mutations in the tyrosinase gene (TYR).
* Stage 2: Conversion of L-tyrosine into dopaquinone by the key enzyme tyrosinase. Subsequent chemical reactions transform dopaquinone into melanin.