tyrosinase

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Related to tyrosinase: tyrosine

mon·o·phe·nol mon·o·ox·y·gen·ase

(mon-ō-fē'nol mon'ō-oksĭ-jen-ās'),

1. A copper-containing oxidoreductase that catalyzes the oxidation of o-diphenols to o-quinones by O₂, with the incorporation of one of the two oxygen atoms in the product; it also catalyzes the oxidation of monophenols, such as l-tyrosine, to dihydroxy-l-phenylalanine (dopa), a precursor of melanin and epinephrine (catecholamines), and can act as a catechol oxidase; a deficiency of this enzyme is observed in several forms of albinism. Synonym(s): cresolase, monophenol oxidase, tyrosinase

2. Synonym(s): laccase

Farlex Partner Medical Dictionary © Farlex 2012

tyrosinase

(tī-rŏs′ə-nās′, -nāz′)

A copper-containing enzyme of plant and animal tissues that catalyzes the production of melanin and other pigments from tyrosine by oxidation, as in the blackening of a peeled or sliced potato exposed to air.

tyrosinase

(1) Catechol oxidase, EC 1.10.3.1.
(2) Monophenol monooxygenase, EC 1.14.18.1.

tyrosinase

A copper-containing enzyme that occurs in melanocytes and catalyses the production of MELANIN from TYROSINE. Also known as monophenol mono-oxygenase.

Collins Dictionary of Medicine © Robert M. Youngson 2004, 2005

Tyrosinase

An enzyme in a pigment cell which helps change tyrosine to DOPA during the process of making melanin.

Mentioned in: Albinism

References in periodicals archive ?

Isolation and characterization of a chicken tyrosinase cDNA.

Mutations of TYR and MITF genes are associated with plumage colour phenotypes in geese

Based on our results, we conclude that VZ-EO is able to suppress the [alpha]-MSH-induced melanogenesis through tyrosinase inactivation and the simultaneous suppression of oxidative stress in B16 melanoma cells.

Effect of Vetiveria zizanioides essential oil on melanogenesis in melanoma cells: downregulation of tyrosinase expression and suppression of oxidative stress

Tyrosinase is diverse in terms of its structural properties, tissue distribution, and cellular location as no common tyrosinase protein structure occurs across all species [34, 35].

Microbial tyrosinases: promising enzymes for pharmaceutical, food bioprocessing, and environmental industry

In addition, thymohydroquinone was found to display higher tyrosinase inhibitory activity (68.82% inhibition at 120 [micro]g/ml) compared to TQ (8.24% inhibition at 166.67 [micro]g/ml) (Lee et al 2011).

Biological, phytochemical, and physico-chemical properties of two commercial Nigella sativa seed oils: A comparative analysis

As shown in Figure 2C, the tyrosinase inhibitory activity of polysaccharides (0.1 ~1 mg/mL) presented a dose-dependent relationship.

Improved antimelanogenesis and antioxidant effects of polysaccharide from Cuscuta chinensis Lam seeds after enzymatic hydrolysis

This study presented the potential AChE, tyrosinase, [alpha]-glucosidase inhibitory effects, total phenolic, total flavonoid contents, the antioxidant effects, and prevention of oxidative DNA damage of leaf, stem bark and fruit of various extracts (L1-8, B1-8 and F1-8) from C.

In Vitro Protection by Crataegus microphylla Extracts Against Oxidative Damage and Enzyme Inhibition Effects/Crataegus microphylla Ekstrelerinin Oksidatif Hasara Karsi In Vitro Koruma ve Enzim Inhibisyonu Etkileri

It inhibits tyrosinase and has anti-inflammatory features.

Current Treatment Approaches for Melasma

Tyrosinase (MW 128 kDa) from Agaricus bisporus, kojic acid ([greater than or equal to]98%), and L-tyrosine were purchased from Sigma-Aldrich (St.

Screening and Characterizing Tyrosinase Inhibitors from Salvia miltiorrhiza and Carthamus tinctorius by Spectrum-Effect Relationship Analysis and Molecular Docking

Before constructing the Lineweaver-Burk plot, the effect of the proso millet extract concentration on tyrosinase activity was determined.

Kinetics Investigation on Mushroom Tyrosinase Inhibition of Proso Millet

The importance of tyrosinase in pigmentation and exoskeleton formation has been demonstrated, suggesting that compounds capable of inhibiting this enzyme could find utility in skin whitening, pest control, and food conservation applications [33-34].

Effects of Fumarprotocetraric Acid, a Depsidone from the Lichen Cladonia verticillaris, on Tyrosinase Activity

OCA type 1 (OCA1) is the most severe and common form of OCA, and is caused by mutations in the tyrosinase gene (TYR).

IDENTIFICATION OF A NOVEL HOMOZYGOUS DELETION OF THE TYROSINASE GENE IN A TURKISH FAMILY WITH OCULOCUTANEOUS ALBINISM TYPE 1

* Stage 2: Conversion of L-tyrosine into dopaquinone by the key enzyme tyrosinase. Subsequent chemical reactions transform dopaquinone into melanin.