type specificity

type specificity

Patient discussion about type specificity

Q. HIV - does it infect specific Blood Types? A friend of mine joined the army and they took him to an experiment and infected him with HIV. But he was not infected- he said because he has a certain blood type. Is this true?

A. HIV, as all other viruses need specific cells,s surface proteins which called receptors,in case of HIV these receptors are found in certain WBCs that known as T-helper cells which named as T4 cells. All humans have these T4 cells but some people lack the receptor that necessary for virus attachment and pentration of the cell which leeds to the inablity of the virus to cause infection and become a target for the immune system. But they c can infect other suseptable people.

More discussions about type specificity
References in periodicals archive ?
A comprehensive characterization of the properties and regulatory activities of enhancers as well as their target genes is therefore crucial to understand the regulation and dysregulation of differentiation, homeostasis and cell type specificity.
Sequences of the hexon gene hypervariable regions 1-6 that provide type specificity (6) showed a single nonsynonymous base substitution (C [right arrow] T; Thr [right arrow] Ile) at nucleotide position 107 of the HAdV-40 prototype strain Dugan (GenBank accession no.
In addition, cross-protection studies in animals (78,83) and observations made in children (84-88) demonstrated that not only type specificity of anti-VP4 and anti-VP7 antibodies but also the level of titres of antibodies were important in protection against disease.
performed with high sensitivity and specificity both in HSV-1-positive and -negative subgroups, underscoring the test's true type specificity.
Organ, tissue and cell type specificity are extremely important in human and other mammalian gene expression analysis," said Tatiana Nikolskaya, chief scientific officer and founder of GeneGo.