type III secretion system


Also found in: Acronyms.

type III secretion system

a syringelike apparatus used by some pathogenic bacteria, such as Yersinia pestis, to penetrate the plasma membrane of a host cell and inject toxin.
References in periodicals archive ?
We further examined the intimin subtype by sequencing the eae gene, the chromosome integration site of the locus of enterocyte effacement encoding the eae gene and a set of type III secretion system genes, and the presence and subtype of the cdtB gene as described (5).
The monoclonal antibody has a unique target mechanism, neutralizing the action of the PcrV protein of the type III secretion system thereby inhibiting a key disease-causing process of Pseudomonas.
They form attaching and effacing lesions on intestinal epithelial cell surfaces by the combined actions of intimin, an eae gene-encoded outer membrane protein, and type III secretion system effectors.
Infection and Immunity, July 2002: Characterization of Salmonella enterica Derivatives Harboring Defined aroC and Salmonella Pathogenicity Island 2 Type III Secretion System (ssaV) Mutations by Immunization of Healthy Volunteers.