The product is a popular ingredient in dermatological products due to its antiallergy, anti-inflammatory, antimicrobial properties, and promotive action on type I and type II collagen
synthesis in tissues.
Articular cartilage is composed of chondrocytes embedded in an extracellular matrix (ECM) formed mainly by type II collagen
and proteoglycan aggrecan molecules, which they synthesize and degrade.
The images of cell viability of 0.125 [micro]g/mL JJYMD-C at 2 days in Figure 6 and of immunohistochemical staining for type II collagen
of control at 2 days in Figure 8 were mistakenly submitted.
The clinical features of spondyloepiphyseal dysplasia congenita resulting from the substitution of glycine 997 by serine in the alpha 1(II) chain of type II collagen
. J Med Genet 1993; 30:27-35.
"Type II collagen
is naturally found in the joint tissue, and studies have shown that hydrolyzed type II collagen
is well absorbed, preferably accumulates in the joint, and helps to activate certain components of cartilage-building cells," she said.
Derived from mesenchymal stem cells (MSCs), chondrocytes are responsible for producing the extracellular matrix that mainly consists of Type II collagen
In addition, research has shown that type II collagen
reduces joint pain and osteoarthritis symptoms.
coli lipopolysaccharide bypasses epitope specificity in the induction of arthritis with monoclonal antibodies to type II collagen
. Autoimmunity 1995; 22: 137-47.
(2003) Stimulation of type II collagen
biosynthesis and secretion in bovine chondrocytes cultured with degraded collagen.
Western blotting showed that aggrecan content of intervertebral discs decreased from Group A (1.88 [+ or -] 0.16) to Group D (0.17 [+ or -] 0.04) with age (P < 0.01); Type II collagen
content of intervertebral discs decreased from Group A (2.22 [+ or -] 0.04) to Group D (0.20 [+ or -] 0.01) with age (P < 0.01).
Type II collagen
was detected by immunofluorescence.