Furthermore, the role of autophagy in antigen presentation after Influenza A infection will be addressed applying an inducible mouse model of autophagy deficiency in alveolar type II cells
, the main target of Influenza A infection in mice.
Consistent with the known function of this promoter, these mice showed expression of IL-13 along the airways and in type II cells
, as shown by mRNA in situ hybridization.
alpha]-Hederin pre-treated alveolar type II cells
(A549) showed an increased [[beta].
Differentiation of MSCs into epithelial type II cells
may partially restore the stem cell pool, leading to increased genesis of alveolar cells for the resolution of disrupted alveolar surfaces, thereby augmenting the repair process.
Endogenous surfactant is normally secreted by alveolar type II cells
, which leaves the alveolar space and reenters the type II cells
in the form of small vesicles.
Consistent with the known effects of alcohol on liver glutathione levels, the researchers first determined that chronic alcohol ingestion in rats dramatically decreases glutathione levels in the alveolar epithelial lining fluid and in the alveolar epithelial type II cells
Triple-label immunofluorescence for Bax, CYP1A1, and cytokeratin 8/18 localizes the expression of Bax and CYP1A1 in alveolar type II cells
(alveolar type II cells
contain abundant cytokeratin 8 and cytokeratin 18).
Type II pneumocytes are surfactant-producing, alveolar epithelial cells and progenitor cells of both type I and type II cells
We found that PA could invade alveolar epithelial type II cells
, and it was mediated by lipid raft activation.
Nasdaq: ALXN) today announced presentation of data showing that the presence of Type II paroxysmal nocturnal hemoglobinuria (PNH) cells is correlated with thrombocytopenia, potentially indicating that patients with Type II cells
experience ongoing platelet consumption and increased thrombosis risk.
Coculture of AMs and alveolar type II cells
, or coculture of AMs and lung fibroblasts, in contact cultures or Transwell chambers, revealed no synergistic effect.
We examined effects of asbestos exposure on the phosphorylation of p53 protein in human pulmonary epithelial type II cells
(A549), which express wild-type p53.