type 1 diabetes mellitus

Also found in: Dictionary, Thesaurus, Encyclopedia.
Related to type 1 diabetes mellitus: Type 2 diabetes mellitus

Type 1 di·a·be·tes

a condition characterized by high blood glucose levels caused by a total lack of insulin. Occurs when the body's immune system attacks the insulin-producing beta cells in the pancreas and destroys them. The pancreas then produces little or no insulin. Type 1 diabetes develops most often in young people but can appear in adults.

type 1 diabetes mellitus

an autoimmune disease characterized by inability to metabolize fuels, carbohydrates, protein, and fat because of absolute insulin deficiency. Type 1 diabetes can occur at any age, but its incidence is more common in children, where it is the most common chronic disease of childhood. Uncontrolled type 1 diabetes is characterized by excessive thirst, increased urination, increased desire to eat, loss of weight, keta acidosis, diminished strength, and marked irritability. The clinical onset is usually rapid, but approximately one third of patients have a remission within 3 months (honeymoon phase). This stage may continue for days or months, but type 1 diabetes then progresses quickly to a state of total dependence on insulin. Persons with type I diabetes can manage their condition with a carbohydrate-controlled meal plan, exercise, and insulin. Evidence suggests that type 1 diabetes may be triggered by environmental factors, such as a viral infection in genetically susceptible individuals. Formerly called brittle diabetes, insulin-dependent diabetes mellitus, juvenile diabetes, juvenile onset diabetes, juvenile onset-type diabetes, ketosis-prone diabetes. Compare type 2 diabetes mellitus. See also diabetes mellitus.

type 1 diabetes mellitus

Brittle DM, insulin-dependent DM, juvenile-onset DM Endocrinology A severe form of DM caused by ↓ endogenous insulin production by the pancreas, which comprises +– 10% of DM Clinical Extreme hyperglycemia, lability of glucose control and ketosis; type 1 DM of recent onset may have IgG autoantibodies against glucose transport proteins. See Honeymoon period. See Diabetes mellitus. Cf type 2 DM.

type 1 diabetes mellitus (formerly known as insulin-dependent diabetes mellitus [IDDM] or juvenile-onset diabetes)

acute-onset disease often affecting younger people (peak age of onset = 12 years); caused by autoimmune destruction of insulin-secreting β cells of pancreas islets of Langerhans and insufficient insulin production; undiagnosed patients show polyuria, polydypsia and glycosuria, leading to severe dehydration, marked weight loss and undue fatigability, history of recurrent infections, ketosis and abnormal respiration (hyperventilation, with smell of acetone on the breath) and tendency to ketoacidotic coma; blood tests show uncontrolled hyperglycaemia, dyslipidaemia (high levels of plasma free fatty acids, cholesterol and triglycerides) and ketoacidosis; patients with type 1 diabetes mellitus require lifelong supplementary insulin

Patient discussion about type 1 diabetes mellitus

Q. Women with diabetes are in general found with type 1 or with type 2 diabetes during pregnancy and why?

A. Women develop gestational diabetes during pregnancy and after pregnancy the gestational diabetes goes, if not this gestational diabetes has chances to develop into type 2 diabetes. A pregnant woman can also have type 1 and 2 diabetes equally and during pregnancy she may get gestational diabetes.

Q. Type 2 Diabetics solution My uncle is suffering from type 2 diabetics and i want to know that is there any permanent solution for type 2 diabities. Very worried about weight loss too. Any one there to give us a permanent solution?

A. Type 2 diabetes is due to improper use of insulin or insulin resistance.

There is a web site given below which provides information on alternative medicines for diabetes. Alternative medicines - ayurveda herbs, homeopathy, yoga and acupressure treatments.

Q. I’m having diabetics for nearly 12 years. Can I eat all types of fruits? I’m 60 years old male and I’m having diabetics for nearly 12 years. I’m taking meds and my sugar is under control. Everyday I have some fruits without fail. Can I eat all types of fruits?

A. Hello sir, surely you can eat any kind of fruit, regardless of the sugar content. The point is you need to spread across the amount of fruits you eat, including a wide variety of different fruits. In general everyone has to eat at least five portions of fruits and vegetables every day. Spreading the fruit you eat through the day will avoid a sudden rise in blood glucose levels.

More discussions about type 1 diabetes mellitus
References in periodicals archive ?
Clinical features at the onset of childhood type 1 diabetes mellitus in Shenyang, China.
a) This occurs more frequently in patients with Type 1 Diabetes Mellitus
M2 EQUITYBITES-January 8, 2014-DiaVacs receives orphan drug designation for type 1 diabetes mellitus therapy
M2 PHARMA-January 8, 2014-DiaVacs receives orphan drug designation for type 1 diabetes mellitus therapy
Physically and mentally handicapped patients, patients of Type 1 diabetes mellitus, patients of chronic renal failure as well as patients on immunosuppressive therapy or who had undergone any transplantation and those using alcohol/smoking were excluded from study.
Down the road, the team will broaden its focus to include other autoimmune disorders with suspected environmental triggers, including rheumatoid arthritis, lupus, type 1 diabetes mellitus, multiple sclerosis, scleroderma (a thickening of the skin), and autoimmune thyroid disease.
Exubera is also indicated for the treatment of adult patients with type 1 diabetes mellitus, in addition to long or intermediate acting injectable insulin, for whom the potential benefits of adding inhaled insulin outweigh the potential safety concerns.
InvestigationsSerum TSH should be assessed in all persons with newly diagnosed type 1 diabetes mellitus after having achieved glycaemic control.
M2 EQUITYBITES-7 June 2010-Kineta Inc receives investment from The Iacocca Family Foundation for Type 1 diabetes mellitus drug development(C)2010 M2 COMMUNICATIONS http://www.