tumourigenesis


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tumourigenesis

The process of tumour development, which requires changes in cellular adhesivity to facilitate disruption of normal tissue architecture and angiogenesis to provide the growing tumour a blood supply.

tu·mor·i·gen·e·sis

(tū'mŏr-i-jen'ĕ-sis)
Production of a new growth or growths.
Synonym(s): tumourigenesis.
[tumor + G. genesis, origin]
References in periodicals archive ?
Increased Polysomies of Chromosome-7 and Chromosome-17 during head and neck multistage tumourigenesis. Cancer Res 1993;53(12):2874-83.
This is supported by the finding that BRAF V600E mutant organoids when orthotopically injected into a murine colon were unable to induce tumourigenesis until further serrated neoplasia-type genetic perturbations were introduced [43].
Thus, we sought to further examine the role that these unannotated and validated miRNAs expressed in kidney tissues may have in ccRCC tumourigenesis and their potential clinical relevance.
Mouradov et al., "Different APC genotypes in proximal and distal sporadic colorectal cancers suggest distinct WNT/[beta]-catenin signalling thresholds for tumourigenesis," Oncogene, vol.
Abas et al., "In situ normoxia enhances survival and proliferation rate of human adipose tissue-derived stromal cells without increasing the risk of tumourigenesis," PLoS One, vol.
Smallwood et al., "Contrasting effects on HIF-1alpha regulation by disease-causing pVHL mutations correlate with patterns of tumourigenesis in von Hippel-Lindau disease," Human Molecular Genetics, vol.
Interestingly, recent studies have shown that HuR knockdown attenuates the oncogenic potential of oral cancer cells [21], whereas a number of studies implicate HuR in the tumourigenesis and progression of head and neck carcinomas.
Keywords: CD44, In vitro, HA receptor, MiR-34-a, Neuroblastoma, Tumourigenesis, Tumour therapy.
Binding of intronic miRNAs to the mRNAs of host genes encoding intronic miRNAs and proteins that participate in tumourigenesis. Comput Biol Med 2013; 43: 1374-1381, doi: 10.1016/ j.compbiomed.2013.07.011.
Molecular genetic investigations of the mechanism of tumourigenesis in von Hippel-Lindau disease: analysis of allele loss in VHL tumours.
Effect of Maitake Pro4X alone or in combination with chemotherapy on mammary tumourigenesis
(16.) ZackularJP, Baxter NT, Iverson KD The gut microbiome modulates colon tumourigenesis. mBio.