tumour-specific antigens

tumour-specific antigens

Substances produced by specific kinds of tumours that can be detected in the blood and may act as indicators or markers of the presence of tumours or of recurrences of tumours. The method is not wholly reliable because these substances can sometimes occur in the body apart from tumours.
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Every patients tumour expresses many shared tumour-specific antigens and bears a highly individual molecular signature comprising 10s to 100s of non-synonymous mutations, many of which are immunogenic.
The new products will be developed from Sorrento's G-MAB library compared with neoepitopes of tumour-specific antigens discovered using NantWorks' pan-omics based, precision medicine approach.
The immune system can target tumour cells for destruction by recognizing tumour-associated or tumour-specific antigens displayed on their surface.
London, January 23 (ANI): Harvard University researchers have shown that small plastic disks, when impregnated with tumour-specific antigens and implanted under the skin, can coax the mammalian immune system to attack tumours.
The expansion will include emerging areas of research in the immune response to tumour neo-antigens, truly tumour-specific antigens that are generated as tumours accumulate genetic mutations.
The tests, Octava Pink and Octava Blue, identify the presence or absence of cancer by assessing ratios of autoantibodies released in response to the presence of tumour-specific antigens.

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