tumour lysis syndrome

The release of cellular breakdown products that occurs when tumour cells are killed by effective anticancer treatment. There is a rise in blood potassium, uric acid and phosphates and a drop in calcium. The effect may be a severe metabolic disturbance that can cause prolonged illness and may prove fatal. Severe kidney damage may occur from urate crystal deposition.

References in periodicals archive ?

Acute tubular necrosis is the most common renal AKI seen in lymphoma patients, with lysozyme-induced tubular necrosis and tumour lysis syndrome being common etiologies (Luciano & Brewster, 2014).

Acute kidney injury secondary to lymphoma

Laboratory tumour lysis syndrome was reported in five people; none had clinical consequences.

Switzerland : Pivotal Phase II study showed nearly 80 percent of people with hard-to-treat type of chronic lymphocytic leukaemia responded to investigational medicine venetoclax

There was no clinical or biochemical evidence of tumour lysis syndrome.

Postoperative internal iliac artery embolisation as salvage therapy for bleeding in an HIV-positive patient with giant cell tumour of bone

A case of metastatic testicular cancer complicated by tumour lysis syndrome and choriocarcinoma syndrome.

Advanced testicular cancer associated with life-threatening tumour lysis syndrome and choriocarcinoma syndrome

The principle of tumour lysis syndrome, prophylaxis/treatment includes virgous hydration, adequate diuresis, control of hyperuricemia with rasburicase or allopurinol, regulation of serum electrolytes and dialysis should be the treatment options.

Tumour lysis syndrome; new approaches at diagnose, follow up and treatment/Tumor lizis sendromu; tani, izlem ve tedavide yeni yaklasimlar

The patient was initiated on chemotherapy but died of acute tumour lysis syndrome [2] days thereafter.

Abdominal Burkitt's lymphoma with renal involvement

The main differential diagnosis was cisplatin hypersensitivity and tumour lysis syndrome (TLS).

Tumour lysis syndrome

Tumour lysis syndrome (TLS) prophylaxis, comprising oral hydration and allopurinol 300 mg/day, was initiated at least three days before initiating lenalidomide and for a minimum of the first three treatment cycles.

Celgene announces interim results from dosing trial of REVLIMID in previously treated CLL patients

Before initiation of EBRT the patient started allopurinol 600 mg/d to prevent tumour lysis syndrome.

Primary breast lymphoma and HIV/AIDS

Acute tumour lysis syndrome following a single-dose corticosteroid in children with acute lymphoblastic leukemia.

Hyperuricemia and tumor lysis syndrome in children with non-Hodgkin's lymphoma and acute lymphoblastic leukemia / Non-Hodgkin lenfoma ve akut lenfoblastik losemili cocuklarda hiperurisemi ve tumor lizis sendromu

Fatal instances of tumour lysis syndrome have been reported during treatment with lenalidomide.

Retrospective Analysis of Clinical Data from REVLIMID[R] Phase III Study (MDS-004) Reports a Significant Improvement in Survival and Risk Reduction in Disease Progression for Patients with del(5Q) Myelodysplastic Syndromes

c) Acute tubular necrosis may be caused by lysozyme-induced tubular necrosis and tumour lysis syndrome